Reply to Murrell et al.: Noise matters

Kinney, J. B., Atwal, G. S. (May 2014) Reply to Murrell et al.: Noise matters. Proceedings of the National Academy of Sciences of the United States of America, 111 (21). E2161. ISSN 10916490

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DOI: 10.1073/pnas.1404661111


The concept of statistical “equitability” plays a central role in the 2011 paper by Reshef et al. (1). Formalizing equitability first requires formalizing the notion of a “noisy functional relationship,” that is, a relationship between two real variables, X and Y, having the form Y=f(X)+η, where f is a function and η is a noise term. Whether a dependence measure satisfies equitability strongly depends on what mathematical properties the noise term η is allowed to have: the narrower one’s definition of noise, the weaker the equitability criterion becomes.

Item Type: Paper
Subjects: bioinformatics
bioinformatics > computational biology
CSHL Authors:
Communities: CSHL labs > Atwal lab
CSHL labs > Kinney lab
Depositing User: Matt Covey
Date: 27 May 2014
Date Deposited: 20 Jun 2014 20:36
Last Modified: 19 Dec 2016 21:48
PMCID: PMC4040606
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