Genetic analyses on DNA microarrays

Stein, L. D. (May 2001) Genetic analyses on DNA microarrays. Curr Protoc Hum Genet, Chapte. Unit 11 .01.

DOI: 10.1002/0471142905.hg1101s24


A great stir has coursed through the genetics community with the advent in 1996 of "chip technologies," a series of related techniques that allow DNA hybridization-based studies to be performed with unprecedented speed and parallelism. All chip technologies have in common a microarray, a small glass chip approximately one square centimeter in area, to which nucleotide sequences are bound. Fluorescently labeled nucleic acids are hybridized to the microarray and imaged with a laser scanner or fluorescence microscope. This unit offers an overview of the two dominant technologies, cDNA microarrays and oligonucleotide chips. It concludes with a discussion regarding how well microarrays perform real-world expression analysis.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > Mapping and Rendering > Micro Array Data Rendering
bioinformatics > genomics and proteomics > analysis and processing > microarray gene expression processing
CSHL Authors:
Communities: CSHL labs > Stein lab
Depositing User: Matt Covey
Date: May 2001
Date Deposited: 16 Jan 2014 17:28
Last Modified: 16 Jan 2014 17:28
Related URLs:

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving