The molecular analysis of synonymy among medically important yeasts within the genus Candida

Wickes, B. L., Hicks, J. B., Merz, W. G., Kwon-Chung, K. J. (1992) The molecular analysis of synonymy among medically important yeasts within the genus Candida. Journal of General Microbiology, 138 (5). pp. 901-907. ISSN 00221287 (ISSN)



Three sets of medically important yeasts, Candida albicans, C. tropicalis, and C. krusei, were compared with their putative synonyms (C. langeronii and C. claussenii, C. paratropicalis, and Itssatchenkia orientalis, respectively) to determine if these synonyms are genetically distinguishable from each other. Pulsed-field electrophoresis and hybridization to species-specific probes were used to accomplish this goal. The species-specific probes for C. albicans and C. tropicalis have been previously described (27A and CT13.8, respectively) whereas the probe for C krusei (CK3) was cloned in this study. No distinguishing characteristics between synonyms were identified, thus supporting the current taxonomic treatment of these organisms.

Item Type: Paper
Uncontrolled Keywords: article candida candida albicans candida krusei candida tropicalis classification genetic analysis hybridization nonhuman priority journal pulsed field gel electrophoresis taxonomy Comparative Study Deoxyribonuclease EcoRI DNA Probes Electrophoresis, Gel, Pulsed-Field Karyotyping Molecular Probe Techniques Mycological Typing Techniques Nucleic Acid Hybridization Polymorphism, Restriction Fragment Length Sequence Homology, Nucleic Acid
Subjects: organism description > yeast
CSHL Authors:
Communities: CSHL labs > Hicks lab
Depositing User: Matt Covey
Date: 1992
Date Deposited: 09 Aug 2013 20:53
Last Modified: 12 Aug 2013 15:21
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