Telomeric and dispersed repeat sequences in Candida yeasts and their use in strain identification

Sadhu, C., McEachern, M. J., Rustchenko-Bulgac, E. P., Schmid, J., Soll, D. R., Hicks, J. B. (1991) Telomeric and dispersed repeat sequences in Candida yeasts and their use in strain identification. Journal of Bacteriology, 173 (2). pp. 842-850. ISSN 00219193 (ISSN)



Several different repetitive DNA sequences have been isolated from the pathogenic yeast Candida albicans. These include two families of large dispersed repeat sequences (Ca3, Ca24) and a short (23-bp) tandemly repeated element (Ca7) associated with C. albicans telomeres. In addition, a large subtelomeric repeat (WOL17) has been cloned. DNA fragments containing the telomeric repeats are highly able among different C. albicans strains. We have shown that the Ca3 repeat is relatively more stable and is suitable for use as a species-specific and strain-specific probe for C. albicans.

Item Type: Paper
Uncontrolled Keywords: article candida albicans dna hybridization dna probe dna sequence molecular cloning nonhuman priority journal Base Sequence Candida Cloning, Molecular DNA, Fungal Gene Library Genes, Fungal Human Molecular Sequence Data Mouth Mucosa Nucleic Acid Hybridization Repetitive Sequences, Nucleic Acid Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S.
Subjects: Investigative techniques and equipment
Corporate Reports
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > telomeres
organism description > yeast
CSHL Authors:
Communities: CSHL labs > Hicks lab
Depositing User: Matt Covey
Date: 1991
Date Deposited: 09 Aug 2013 20:56
Last Modified: 12 Aug 2013 14:46
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