Additional materials of the author at
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Dantas, Ezequiel, Murthy, Anirudh, Ahmed, Tanvir, Ahmed, Mujmmail, Ramsamooj, Shakti, Hurd, Maurice A, Lam, Tiffany, Malbari, Murtaza, Agrusa, Christopher, Elemento, Olivier, Zhang, Chen, Pappin, Darryl J, McGraw, Timothy E, Stiles, Brendon M, Altorki, Nasser K , Goncalves, Marcus D (2023) TIMP1 is an early biomarker for detection and prognosis of lung cancer. Clinical and Translational Medicine, 13(10) pp. e1391.

Yao, Min, Preall, Jonathan, Yeh, Johannes, Pappin, Darryl J, Cifani, Paolo, Zhao, Yixin, Shen, Sophia, Moresco, Philip, He, Brian, Patel, Hardik, Habowski, Amber N, King, Daniel A, Raphael, Kara L, Rishi, Arvind, Sejpal, Divyesh V, Weiss, Matthew, Tuveson, David , Fearon, Douglas T (2023) Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens. JCI Insight, pp. e172449.

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ , Tonks, NicholasK (2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry, pp. 104582. Elsevier BV.

Yu, Allen T, Aggarwal, Disha, Pappin, Darryl , Spector, David L (2022) Single Oligonucleotide Capture of RNA And Temperature Elution Series ( SOCRATES ) for Identification of RNA-binding Proteins. Bio-protocol, 12(24) pp. e4572.

Paul, Shilpi, Cifani, Paolo, Pappin, Darryl , Spratt, Thomas (2022) Unique DNA Polymerase kappa Interactome Suggests Novel Cellular Functions. The FASEB Journal, 36 Sup(S1)

Paul, Shilpi, Rebok, Abbey, Cifani, Paolo, Paul, Anirban, Pappin, Darryl, Huang, Tony , Spratt, Thomas (2022) Translesion DNA synthesis polymerase κ is essential to a carcinogen-induced nucleolar stress response. bioRxiv,

Sagabala, Reddy S, Londhe, Avinash D, Marquart, Krisann, Pappin, Darryl , Boivin, Benoit (2022) Role of PTP1B in the Regulation of Cholesterol Homeostasis. The FASEB Journal, 36(S1)

Lee, Yu-Chen, Lin, Song-Chang, Yu, Guoyu, Zhu, Ming, Song, Jian H, Rivera, Keith, Pappin, Darryl J, Logothetis, Christopher J, Panaretakis, Theocharis, Wang, Guocan, Yu-Lee, Li-Yuan , Lin, Sue-Hwa (2021) Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition. Oncogene,

Lee, Yu-Chen, Lin, Song-Chang, Yu, Guoyu, Zhu, Ming, Song, Jian, Rivera, Keith, Pappin, Darryl, Logothetis, Christopher, Panaretakis, Theocharis, Wang, Guocan, Yu-Lee, Li-Yuan , Lin, Sue-Hwa (2021) Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition. BioRxiv,

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda , Tuveson, David A (2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.. Proceedings of the National Academy of Sciences of USA, 118(21) pp. e2016904118-e2016904118.

Yu, Allen T, Berasain, Carmen, Bhatia, Sonam, Rivera, Keith, Liu, Bodu, Rigo, Frank, Pappin, Darryl J , Spector, David L (2021) PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR. eLife, 10

Yu, Allen, Berasain, Carmen, Bhatia, Sonam, Rivera, Keith, Liu, Bodu, Rigo, Frank, Pappin, Darryl , Spector, David (2021) PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR. bioRxiv,

Chang, K. C., Diermeier, S. D., Yu, A. T., Brine, L. D., Russo, S., Bhatia, S., Alsudani, H., Kostroff, K., Bhuiya, T., Brogi, E., Pappin, D. J., Bennett, C. F., Rigo, F. , Spector, D. L. (2020) MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression. Nat Commun, 11(1) pp. 6438.

Cheng, D. K., Oni, T. E., Park, Y., Thalappillil, J. S, Ting, H.-C., Alagesan, B., Prasad, N. V., Rivera, K. D., Pappin, D. J., Van Aelst, L. , Tuveson, D. A. (2020) Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer. BioRxiv,

Oni, Tobiloba E, Bautista, Carmelita, Merrill, Joseph R, Goos, Jeroen ACM, Rivera, Keith D, Miyabayashi, Koji, Biffi, Giulia, Garcia, Libia, Plenker, Dennis, Patel, Hardik, Elyada, Ela, Samaritano, Maria, Yu, Kenneth H, Pappin, Darryl J, Goggins, Michael G, Hruban, Ralph H, Lewis, Jason S, Lyons, Scott K, Yeh, Johannes T , Tuveson, David A (2020) Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models. BioRxiv,

Bencze, G., Bencze, S., Rivera, K. D., Watson, J. D., Orfi, L., Tonks, N. K. , Pappin, D. J. (2020) Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. Sci Rep, 10(1) pp. 14174.

Wilson, J., Palmeri, J. , Pappin, D. (2020) SimpliFi: a data-to-meaning analytics engine to bring omics understanding to all. J Biomol Tech, 31(Suppl) pp. S1.

Wilson, J.P., Ipsaro, J. J., Del Giudice, S.N., Turna, N. S., Gauss, C. M., Dusenbury, K.H., Marquart, K., Rivera, K. D. , Pappin, D. J. (2020) Tryp-N: A Thermostable Protease for the Production of N-terminal Argininyl and Lysinyl Peptides. J Proteome Res, 19(4) pp. 1459-1469.

Marchione, D. M., Ilieva, I., Devins, K., Sharpe, D., Pappin, D. J., Garcia, B. A., Wilson, J. P. , Wojcik, J. B. (2020) HYPERsol: High-Quality Data from Archival FFPE Tissue for Clinical Proteomics. J Proteome Res, 19(2) pp. 973-983.

Londhe, A. D., Bergeron, A., Curley, S. M., Zhang, F., Rivera, K. D., Kannan, A., Coulis, G., Rizvi, S. H. M., Kim, S. J., Pappin, D. J., Tonks, N. K., Linhardt, R. J. , Boivin, B. (2019) Regulation of PTP1B activation through disruption of redox-complex formation. Nat Chem Biol, 16(2) pp. 122-125.

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Da Silva, B., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grutzmann, R., Aust, D., Gimotty, P. A., Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A. , Tuveson, D. A. (2019) The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science, 364(6446) pp. 1156-1162.

Melnikov, S. V., Manakongtreecheep, K., Rivera, K. D., Makarenko, A., Pappin, D. J. , Soll, D. (2018) Muller's Ratchet and Ribosome Degeneration in the Obligate Intracellular Parasites Microsporidia. Int J Mol Sci, 19(12)

Parrine, D., Wu, B. S., Muhammad, B., Rivera, K., Pappin, D., Zhao, X. , Lefsrud, M. (2018) Proteome modifications on tomato under extreme high light induced-stress. Proteome Science, 16(1) pp. Article no 20.

Melnikov, S. V., Rivera, K. D., Ostapenko, D., Makarenko, A., Sanscrainte, N. D., Becnel, J. J., Solomon, M. J., Texier, C., Pappin, D. J. , Soll, D. (2018) Error-prone protein synthesis in parasites with the smallest eukaryotic genome. Proc Natl Acad Sci U S A, 115(27) pp. E6245-6253.

Krishnan, N., Felice, C., Rivera, K., Pappin, D. J. , Tonks, N. K. (2018) DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease. Genes Dev, 32(13-14) pp. 944-952.

Naguib, A., Mathew, G., Reczek, C. R., Watrud, K., Ambrico, A., Herzka, T., Salas, I. C., Lee, M. F., El-Amine, N., Zheng, W., Di Francesco, M. E., Marszalek, J. R., Pappin, D. J., Chandel, N. S. , Trotman, L. C. (2018) Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells. Cell Rep, 23(1) pp. 58-67.

Lee, Y. C., Baath, J. A., Bastle, R. M., Bhattacharjee, S., Cantoria, M. J., Dornan, M., Gamero-Estevez, E., Ford, L., Halova, L., Kernan, J., Kurten, C., Li, S., Martinez, J., Sachan, N., Sarr, M., Shan, X., Subramanian, N., Rivera, K., Pappin, D. , Lin, S. H. (2018) Impact of Detergents on Membrane Protein Complex Isolation. J Proteome Res, 17(1) pp. 348-358.

Wilson, J., Turna, N. S., Banks, R., Pappin, D. J. C. , Zougman, A. (2017) Clinical applications of universal S-Trap sample processing. Molecular & Cellular Proteomics, 16(8; Sup) pp. S56-S56.

Pattison, S. H., Gibson, D. S., Johnston, E., Peacock, S., Rivera, K., Tunney, M. M., Pappin, D. J. , Elborn, J. S. (2017) Proteomic profile of cystic fibrosis sputum cells in adults chronically infected with Pseudomonas aeruginosa. Eur Respir J, 50(1)

Chio, I. I. C., Jafarnejad, S. M., Ponz-Sarvise, M., Park, Y., Rivera, K., Palm, W., Ohlund, D., Hammell, M., Crawford, H., Schmidt, E., Thompson, C., Pappin, D., Sonenberg, N. , Tuveson, D. (2017) NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer. Cancer Research, 77(Supple)

Chio, Iok In Christine, Jafarnejad, Seyed Mehdi, Ponz-Sarvise, Mariano, Park, Youngkyu, Rivera, Keith, Palm, Wilhelm, Wilson, John, Sangar, Vineet, Hao, Yuan, Öhlund, Daniel, Wright, Kevin, Filippini, Dea, Lee, Eun Jung, Da Silva, Brandon, Schoepfer, Christina, Wilkinson, John Erby, Buscaglia, Jonathan M, DeNicola, Gina M, Tiriac, Herve, Hammell, Molly, Crawford, Howard C, Schmidt, Edward E, Thompson, Craig B, Pappin, Darryl J, Sonenberg, Nahum , Tuveson, David A (2016) NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell, 166(4) pp. 963-976.

Herrera, V. L., Steffen, M., Moran, A. M., Tan, G. A., Pasion, K. A., Rivera, K., Pappin, D. J. , Ruiz-Opazo, N. (2016) Confirmation of translatability and functionality certifies the dual endothelin1/VEGFsp receptor (DEspR) protein. BMC Mol Biol, 17(1) pp. 15.

Ho, J. M., Reynolds, N. M., Rivera, K., Connolly, M., Guo, L. T., Ling, J. Q., Pappin, D. J., Church, G. M. , Soll, D. (2016) Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli. ACS Synthetic Biology, 5(2) pp. 163-171.

Shen, Chen, Ipsaro, Jonathan J, Shi, Junwei, Milazzo, Joseph P, Wang, Eric, Roe, Jae-Seok, Suzuki, Yutaka, Pappin, Darryl J, Joshua-Tor, Leemor , Vakoc, Christopher R (2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell, 60(6) pp. 847-859.

Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, II, Giannopoulou, E. G., Rago, C., Muley, A., Asara, J. M., Paik, J., Elemento, O., Chen, Z., Pappin, D. J., Dow, L. E., Papadopoulos, N., Gross, S. S. , Cantley, L. C. (2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science, 350(6266) pp. 1391-1396.

Roe, Jae-Seok, Mercan, Fatih, Rivera, Keith, Pappin, Darryl J , Vakoc, Christopher R (2015) BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia. Molecular Cell, 58(6) pp. 1028-1036.

Akerman, M., Fregoso, O. I., Das, S., Ruse, C., Jensen, M. A., Pappin, D. J., Zhang, M. Q. , Krainer, A. R. (2015) Differential connectivity of splicing activators and repressors to the human spliceosome. Genome Biol, 16(1) pp. 119.

Naguib, Adam, Bencze, Gyula, Cho, Hyejin, Zheng, Wu, Tocilj, Ante, Elkayam, Elad, Faehnle, Christopher R, Jaber, Nadia, Pratt, Christopher P, Chen, Muhan, Zong, Wei-Xing, Marks, Michael S, Joshua-Tor, Leemor, Pappin, Darryl J , Trotman, Lloyd C (2015) PTEN Functions by Recruitment to Cytoplasmic Vesicles. Molecular Cell, 58(2) pp. 255-268.

Fan, G., Wrzeszczynski, K. O., Fu, C., Su, G., Pappin, D. J., Lucito, R. , Tonks, N. K. (2015) A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines. Biochem J, 465(3) pp. 433-42.

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H M., Molenaar, I.  Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert G J., Clevers, Hans , Tuveson, David A (2015) Organoid Models of Human and Mouse Ductal Pancreatic Cancer. Cell, 160(1-2) pp. 324-338.

Naguib, A., Bencze, G., Engle, D. D., Chio, II, Herzka, T., Watrud, K., Bencze, S., Tuveson, D. A., Pappin, D. J. , Trotman, L. C. (2014) P53 Mutations Change Phosphatidylinositol Acyl Chain Composition. Cell Reports, 10(1) pp. 8-19.

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B. , Tonks, N. K. (2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55(5) pp. 782-790.

Ruse, C. I., Peacock, S., Ghiban, C., Rivera, K., Pappin, D. J. , Leopold, P. (2013) A tool to evaluate correspondence between extraction ion chromatographic peaks and peptide-spectrum matches in shotgun proteomics experiments. Proteomics, 13(16) pp. 2386-2397.

Naguib, A., Bencze, G., Faehnle, C. R., Schalch, T., Lazar, Z., Ruse, C. I., Joshua-Tor, L., Pappin, D. J. , Trotman, L. C. (2013) Upstream activation of PTEN. Cancer Research, 73(8 (Sup) pp. 5156.

Wrzeszczynski, K. O., Fan, G. F., Fu, C. X., Pappin, D. J., Lucito, R. , Tonks, N. K. (2013) Proteomic identification of carboplatin resistance in ovarian cancer cells. Cancer Research, 73(8 Supp) pp. 2502.

Miething, C., Scuoppo, C., Lindqvist, L., Reyes, J., Ruse, C., Appelmann, I., Yoon, S., Krasnitz, A., Teruya-Feldstein, J., Pappin, D., Pelletier, J. , Lowe, S. (2012) An oncogenome-based RNAi screen identifies a tumour suppressor network in B-cell lymphoma relying on the polyamine-hypusine axis. Onkologie, 35 pp. 104-104.

Scuoppo, C., Miething, C., Lindqvist, L., Reyes, J., Ruse, C., Appelmann, I., Yoon, S., Krasnitz, A., Teruya-Feldstein, J., Pappin, D., Pelletier, J. , Lowe, S. W. (2012) A tumour suppressor network relying on the polyamine-hypusine axis. Nature, 487(7406) pp. 244-8.

Krishnan, N., Fu, C., Pappin, D. J. , Tonks, N. K. (2011) H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response. Science Signaling, 4(203)

Obad, S., Dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., Fu, C., Lindow, M., Stenvang, J., Straarup, E. M., Hansen, H. F., Koch, T., Pappin, D., Hannon, G. J. , Kauppinen, S. (2011) Silencing of microRNA families by seed-targeting tiny LNAs. Nature Genetics, 43(4) pp. 371-380.

Haase, A. D., Fenoglio, S., Muerdter, F., Guzzardo, P. M., Czech, B., Pappin, D. J., Chen, C., Gordon, A. , Hannon, G. J. (2010) Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila. Genes and Development, 24(22) pp. 2499-2504.

Kirchner, M., Renard, B. Y., Kothe, U., Pappin, D. J., Hamprecht, F. A., Steen, H. , Steen, J. A. J. (2010) Computational protein profile similarity screening for quantitative mass spectrometry experiments. Bioinformatics, 26(1) pp. 77-83.

Boersema, P. J., Taouatas, N., Altelaar, A. F. M., Gouw, J. W., Ross, P. L., Pappin, D. J., Heck, A. J. R. , Mohammed, S. (2009) Straightforward and de Novo Peptide Sequencing by MALDI-MS/MS Using a Lys-N Metalloendopeptidase. Molecular & Cellular Proteomics, 8(4) pp. 650-660.

Han, H., Pappin, D. J., Ross, P. L. , McLuckey, S. A. (2008) Electron transfer dissociation of iTRAQ labeled peptide ions. J Proteome Res, 7(9) pp. 3643-8.

Choe, L., D'Ascenzo, M., Relkin, N. R., Pappin, D., Ross, P., Williamson, B., Guertin, S., Pribil, P. , Lee, K. H. (2007) 8-plex quantitation of changes in cerebrospinal fluid protein expression in subjects undergoing intravenous immunoglobulin treatment for Alzheimer's disease. Proteomics, 7(20) pp. 3651-60.

Henderson, M. J., Munoz, M. A., Saunders, D. N., Clancy, J. L., Russell, A. J., Williams, B., Pappin, D., Khanna, K. K., Jackson, S. P., Sutherland, R. L. , Watts, C. K. (2006) EDD mediates DNA damage-induced activation of CHK2. J Biol Chem, 281(52) pp. 39990-40000.

Zhang, Y., Wolf-Yadlin, A., Ross, P. L., Pappin, D. J., Rush, J., Lauffenburger, D. A. , White, F. M. (2005) Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. Mol Cell Proteomics, 4(9) pp. 1240-50.

Ross, P. L., Huang, Y. N., Marchese, J. N., Williamson, B., Parker, K., Hattan, S., Khainovski, N., Pillai, S., Dey, S., Daniels, S., Purkayastha, S., Juhasz, P., Martin, S., Bartlet-Jones, M., He, F., Jacobson, A. , Pappin, D. J. (2004) Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics, 3(12) pp. 1154-69.

Smirnov, I. P., Zhu, X., Taylor, T., Huang, Y., Ross, P., Papayanopoulos, I. A., Martin, S. A. , Pappin, D. J. (2004) Suppression of alpha-cyano-4-hydroxycinnamic acid matrix clusters and reduction of chemical noise in MALDI-TOF mass spectrometry. Anal Chem, 76(10) pp. 2958-65.

Wu, Y., Egerton, G., Pappin, D. J., Harrison, R. A., Wilkinson, M. C., Underwood, A. , Bianco, A. E. (2004) The Secreted Larval Acidic Proteins (SLAPs) of Onchocerca spp. are encoded by orthologues of the alt gene family of Brugia malayi and have host protective potential. Mol Biochem Parasitol, 134(2) pp. 213-24.

Goldberg, M., Stucki, M., Falck, J., D'Amours, D., Rahman, D., Pappin, D., Bartek, J. , Jackson, S. P. (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature, 421(6926) pp. 952-6.

Diao, A., Rahman, D., Pappin, D. J., Lucocq, J. , Lowe, M. (2003) The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation. Journal of Cell Biology, 160(2) pp. 201-12.

Unwin, R. D., Harnden, P., Pappin, D., Rahman, D., Whelan, P., Craven, R. A., Selby, P. J. , Banks, R. E. (2003) Serological and proteomic evaluation of antibody responses in the identification of tumor antigens in renal cell carcinoma. Proteomics, 3(1) pp. 45-55.

Pappin, D. J. (2003) Peptide mass fingerprinting using MALDI-TOF mass spectrometry. Methods in Molecular Biology, 211 pp. 211-9.

Uchiyama, K., Jokitalo, E., Kano, F., Murata, M., Zhang, X., Canas, B., Newman, R., Rabouille, C., Pappin, D., Freemont, P. , Kondo, H. (2002) VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J Cell Biol, 159(5) pp. 855-66.

Zegerman, P., Canas, B., Pappin, D. , Kouzarides, T. (2002) Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J Biol Chem, 277(14) pp. 11621-4.

Ragno, S., Romano, M., Howell, S., Pappin, D. J., Jenner, P. J. , Colston, M. J. (2001) Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. Immunology, 104(1) pp. 99-108.

Corrigall, V. M., Bodman-Smith, M. D., Fife, M. S., Canas, B., Myers, L. K., Wooley, P., Soh, C., Staines, N. A., Pappin, D. J., Berlo, S. E., van Eden, W., van Der Zee, R., Lanchbury, J. S. , Panayi, G. S. (2001) The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis. J Immunol, 166(3) pp. 1492-8.

Banks, R. E., Dunn, M. J., Hochstrasser, D. F., Sanchez, J. C., Blackstock, W., Pappin, D. J. , Selby, P. J. (2000) Proteomics: new perspectives, new biomedical opportunities. Lancet, 356(9243) pp. 1749-56.

Perraudeau, M., Taylor, P. R., Stauss, H. J., Lindstedt, R., Bygrave, A. E., Pappin, D. J., Ellmerich, S., Whitten, A., Rahman, D., Canas, B., Walport, M. J., Botto, M. , Altmann, D. M. (2000) Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice. Eur J Immunol, 30(10) pp. 2871-80.

Hanakahi, L. A., Bartlet-Jones, M., Chappell, C., Pappin, D. , West, S. C. (2000) Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair. Cell, 102(6) pp. 721-9.

Meyer, H. H., Shorter, J. G., Seemann, J., Pappin, D. , Warren, G. (2000) A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J, 19(10) pp. 2181-92.

Navaratnam, D. S., Fernando, F. S., Priddle, J. D., Giles, K., Clegg, S. M., Pappin, D. J., Craig, I. , Smith, A. D. (2000) Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization. J Neurochem, 74(5) pp. 2146-53.

van Ham, M., van Lith, M., Lillemeier, B., Tjin, E., Gruneberg, U., Rahman, D., Pastoors, L., van Meijgaarden, K., Roucard, C., Trowsdale, J., Ottenhoff, T., Pappin, D. , Neefjes, J. (2000) Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO. J Exp Med, 191(7) pp. 1127-36.

Reeves, E. P., Dekker, L. V., Forbes, L. V., Wientjes, F. B., Grogan, A., Pappin, D. J. , Segal, A. W. (1999) Direct interaction between p47phox and protein kinase C: evidence for targeting of protein kinase C by p47phox in neutrophils. Biochemical Journal, 344 Pt pp. 859-66.

Perkins, D. N., Pappin, D. J., Creasy, D. M. , Cottrell, J. S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis, 20(18) pp. 3551-67.

Young, J. D., Lawrence, A. J., MacLean, A. G., Leung, B. P., McInnes, I. B., Canas, B., Pappin, D. J. , Stevenson, R. D. (1999) Thymosin beta 4 sulfoxide is an anti-inflammatory agent generated by monocytes in the presence of glucocorticoids. Nature Medicine, 5(12) pp. 1424-7.

Karimi-Busheri, F., Daly, G., Robins, P., Canas, B., Pappin, D. J., Sgouros, J., Miller, G. G., Fakhrai, H., Davis, E. M., Le Beau, M. M. , Weinfeld, M. (1999) Molecular characterization of a human DNA kinase. Journal of Biological Chemistry, 274(34) pp. 24187-94.

Hoss, M., Robins, P., Naven, T. J., Pappin, D. J., Sgouros, J. , Lindahl, T. (1999) A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein. EMBO Journal, 18(13) pp. 3868-75.

Banks, R. E., Dunn, M. J., Forbes, M. A., Stanley, A., Pappin, D., Naven, T., Gough, M., Harnden, P. , Selby, P. J. (1999) The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis--preliminary findings. Electrophoresis, 20(4-5) pp. 689-700.

Hanley, S. Z., Pappin, D. J., Rahman, D., White, A. J., Elborough, K. M. , Slabas, A. R. (1999) Re-evaluation of the primary structure of Ralstonia eutropha phasin and implications for polyhydroxyalkanoic acid granule binding. FEBS Letters, 447(1) pp. 99-105.

Lowe, M., Rabouille, C., Nakamura, N., Watson, R., Jackman, M., Jamsa, E., Rahman, D., Pappin, D. J. , Warren, G. (1998) Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis. Cell, 94(6) pp. 783-93.

Mason, G. G., Murray, R. Z., Pappin, D. , Rivett, A. J. (1998) Phosphorylation of ATPase subunits of the 26S proteasome. FEBS Letters, 430(3) pp. 269-74.

Banks, R. E., Forbes, M. A., Searles, J., Pappin, D., Canas, B., Rahman, D., Kaufmann, S., Walters, C. E., Jackson, A., Eves, P., Linton, G., Keen, J., Walker, J. J. , Selby, P. J. (1998) Evidence for the existence of a novel pregnancy-associated soluble variant of the vascular endothelial growth factor receptor, Flt-1. Molecular Human Reproduction, 4(4) pp. 377-86.

van Ham, S. M., Tjin, E. P., Lillemeier, B. F., Gruneberg, U., van Meijgaarden, K. E., Pastoors, L., Verwoerd, D., Tulp, A., Canas, B., Rahman, D., Ottenhoff, T. H., Pappin, D. J., Trowsdale, J. , Neefjes, J. (1997) HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. Curr Biol, 7(12) pp. 950-7.

Cotterill, L. A., Stauss, H. J., Millrain, M. M., Pappin, D. J., Rahman, D., Canas, B., Chandler, P., Stackpoole, A., Simpson, E., Robinson, P. J. , Dyson, P. J. (1997) Qa-1 interaction and T cell recognition of the Qa-1 determinant modifier peptide. European Journal of Immunology, 27(9) pp. 2123-32.

Kondo, H., Rabouille, C., Newman, R., Levine, T. P., Pappin, D., Freemont, P. , Warren, G. (1997) p47 is a cofactor for p97-mediated membrane fusion. Nature, 388(6637) pp. 75-8.

Rodriguez-Viciana, P., Warne, P. H., Khwaja, A., Marte, B. M., Pappin, D., Das, P., Waterfield, M. D., Ridley, A. , Downward, J. (1997) Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell, 89(3) pp. 457-67.

Gut, I. G., Jeffery, W. A., Pappin, D. J. C. , Beck, S. (1997) Analysis of DNA by 'charge tagging' and matrix-assisted laser desorption/ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 11(1) pp. 43-50.

Pappin, D. J. (1997) Peptide mass fingerprinting using MALDI-TOF mass spectrometry. Methods in molecular biology (Clifton, N.J.), 64 pp. 165-173.

Spengler, B., Luetzenkirchen, F., Metzger, S., Chaurand, P., Kaufmann, R., Jeffery, W., Bartlet-Jones, M. , Pappin, D. J. C. (1997) Peptide sequencing of charged derivatives by postsource decay MALDI mass spectrometry. International Journal of Mass Spectrometry and Ion Processes, 169-17 pp. 127-140.

Coffer, A., Cavailles, V., Knowles, P. , Pappin, D. (1996) Biochemical characterization and novel isolation of pure estrogen receptor hormone-binding domain. J Steroid Biochem Mol Biol, 58(5-6) pp. 467-77.

Blackford, J., Reid, H. W., Pappin, D. J., Bowers, F. S. , Wilkinson, J. M. (1996) A monoclonal antibody, 3/22, to rabbit CD11c which induces homotypic T cell aggregation: evidence that ICAM-1 is a ligand for CD11c/CD18. Eur J Immunol, 26(3) pp. 525-31.

Salmeron, A., Ahmad, T. B., Carlile, G. W., Pappin, D., Narsimhan, R. P. , Ley, S. C. (1996) Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. Embo Journal, 15(4) pp. 817-26.

Otto, W. R., Rao, J., Cox, H. M., Kotzian, E., Lee, C. Y., Goodlad, R. A., Lane, A., Gorman, M., Freemont, P. A., Hansen, H. F., Pappin, D. , Wright, N. A. (1996) Effects of pancreatic spasmolytic Polypeptide (PSP) on epithelial cell function. European Journal of Biochemistry, 235(1-2) pp. 64-72.

Palmer, R. H., Schonwasser, D. C., Rahman, D., Pappin, D. J., Herget, T. , Parker, P. J. (1996) PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163. Febs Letters, 378(3) pp. 281-5.

Lahooti, H., White, R., Hoare, S. A., Rahman, D., Pappin, D. J. , Parker, M. G. (1995) Identification of phosphorylation sites in the mouse oestrogen receptor. J Steroid Biochem Mol Biol, 55(3-4) pp. 305-13.

Herget, T., Oehrlein, S. A., Pappin, D. J., Rozengurt, E. , Parker, P. J. (1995) The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C. Eur J Biochem, 233(2) pp. 448-57.

Bishop, L. A., Rahman, D., Pappin, D. J. , Watt, F. M. (1995) Identification of an 80kD protein associated with the alpha 3 beta 1 integrin as a proteolytic fragment of the alpha 3 subunit: studies with human keratinocytes. Cell Adhes Commun, 3(3) pp. 243-55.

Wei, Y. F., Robins, P., Carter, K., Caldecott, K., Pappin, D. J., Yu, G. L., Wang, R. P., Shell, B. K., Nash, R. A. , Schar, P. (1995) Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol Cell Biol, 15(6) pp. 3206-16.

Sutton, C. W., Pemberton, K. S., Cottrell, J. S., Corbett, J. M., Wheeler, C. H., Dunn, M. J. , Pappin, D. J. (1995) Identification of myocardial proteins from two-dimensional gels by peptide mass fingerprinting. Electrophoresis, 16(3) pp. 308-316.

Robins, P., Pappin, D. J., Wood, R. D. , Lindahl, T. (1994) Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I. J Biol Chem, 269(46) pp. 28535-8.

Kiefer, P., Acland, P., Pappin, D., Peters, G. , Dickson, C. (1994) Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3. EMBO J, 13(17) pp. 4126-36.

Bartlet-Jones, M., Jeffery, W. A., Hansen, H. F. , Pappin, D. J. (1994) Peptide ladder sequencing by mass spectrometry using a novel, volatile degradation reagent. Rapid Commun Mass Spectrom, 8(9) pp. 737-42.

Ley, S. C., Verbi, W., Pappin, D. J., Druker, B., Davies, A. A. , Crumpton, M. J. (1994) Tyrosine phosphorylation of alpha tubulin in human T lymphocytes. Eur J Immunol, 24(1) pp. 99-106.

Lovering, R., Hanson, I. M., Borden, K. L., Martin, S., O'Reilly, N. J., Evan, G. I., Rahman, D., Pappin, D. J., Trowsdale, J. , Freemont, P. S. (1993) Identification and preliminary characterization of a protein motif related to the zinc finger. Proc Natl Acad Sci U S A, 90(6) pp. 2112-6.

Pappin, D. J. C., Hojrup, P. , Bleasby, A. J. (1993) Rapid identification of proteins by peptide-mass fingerprinting. Current Biology, 3(6) pp. 327-332.

Beck, S., Hanson, I., Kelly, A., Pappin, D. J. , Trowsdale, J. (1992) A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC. DNA Seq, 2(4) pp. 203-10.

Coffer, A., Fellows, J., Young, S., Pappin, D. , Rahman, D. (1991) Purification and characterization of biologically active scatter factor from ras-transformed NIH 3T3 conditioned medium. Biochem J, 278 ( pp. 35-41.

Bodwell, J. E., Orti, E., Coull, J. M., Pappin, D. J., Smith, L. I. , Swift, F. (1991) Identification of phosphorylated sites in the mouse glucocorticoid receptor. J Biol Chem, 266(12) pp. 7549-55.

Coull, J. M., Pappin, D. J., Mark, J., Aebersold, R. , Koster, H. (1991) Functionalized membrane supports for covalent protein microsequence analysis. Anal Biochem, 194(1) pp. 110-20.

Robson, C. N., Milne, A. M., Pappin, D. J. , Hickson, I. D. (1991) Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damage in vitro: homology with bacterial repair enzymes. Nucleic Acids Res, 19(5) pp. 1087-92.

Pappin, D. J., Coull, J. M. , Koster, H. (1990) Solid-phase sequence analysis of proteins electroblotted or spotted onto polyvinylidene difluoride membranes. Anal Biochem, 187(1) pp. 10-9.

Coull, J. M. , Pappin, D. J. (1990) A rapid fluorescent staining procedure for proteins electroblotted onto PVDF membranes. Journal of Protein Chemistry, 9 pp. 259.

Wales, R., Newman, B. J., Rose, S. A., Pappin, D. , Gray, J. C. (1989) Characterization of cDNA clones encoding the extrinsic 23 kDa polypeptide of the oxygen-evolving complex of photosystem II in pea. Plant Mol Biol, 13(5) pp. 573-82.

Koh-Luar, S. I., Parish, J. H., Bleasby, A. J., Pappin, D. J. C., Ainley, K., Johansen, F. E., McPherson, M. J. , Radfors, A. (1989) Exported proteins of Neurospora crassa: 1-glucoamylase. Enzyme and Microbial Technology, 11(10) pp. 692-695.

Wales, R., Newman, B. J., Pappin, D. , Gray, J. C. (1989) The extrinsic 33 kDa polypeptide of the oxygen-evolving complex of photosystem II is a putative calcium-binding protein and is encoded by a multi-gene family in pea. Plant Molecular Biology, 12(4) pp. 439-451.

Wallace, T. P., Stewart, A. C., Pappin, D. , Howe, C. J. (1989) Gene sequence for the 9 kDa component of Photosystem II from the cyanobacterium Phormidium laminosum indicates similarities between cyanobacterial and other leader sequences. Molecular & General Genetics, 216(2-3) pp. 334-339.

Shewry, P. R., Tatham, A. S., Pappin, D. J. , Keen, J. (1988) N-terminal amino-acid sequences show that D-hordein of barley and high molecular-weight (HMW) secalins of rye are homologous with HMW glutenin subunits of wheat. Cereal Chemistry, 65(6) pp. 510-511.

March, J. F., Pappin, D. J. , Casey, R. (1988) Isolation and characterization of a minor legumin and its constituent polypeptides from Pisum sativum (pea). Biochem J, 250(3) pp. 911-5.

Dunn, P. P., Packman, L. C., Pappin, D. J. , Gray, J. C. (1988) N-terminal amino acid sequence analysis of the subunits of pea photosystem I. Febs Letters, 228(1) pp. 157-61.

Bowles, D. J. , Pappin, D. J. (1988) Traffic and assembly of concanavalin A. Trends Biochem Sci, 13(2) pp. 60-4.

Findlay, J. B. C., Pappin, D. J. , Eliopoulos, E. E. (1988) The primary structure, chemistry and molecular modelling of rhodopsin. Progress in Retinal Research, 7 pp. 63-87.

Keen, Jeffrey N., Pappin, Darryl J. C. , Evans, Leonard V. (1988) Amino Acid Sequence Analysis Of The Small Subunit Of Ribulose Bisphosphate Carboxylase From Fucus (Phaeophyceae)1. Journal of Phycology, 24(3) pp. 324-327.

Hooper, N. M., Keen, J., Pappin, D. J. , Turner, A. J. (1987) Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane. Biochem J, 247(1) pp. 85-93.

Shewry, P. R., Parmar, S. , Pappin, D. J. (1987) Characterization and genetic control of the prolamins of Haynaldia villosa: relationship to cultivated species of the Triticeae (rye, wheat, and barley). Biochem Genet, 25(3-4) pp. 309-25.

Cavaggioni, A., Sorbi, R. T., Keen, J. N., Pappin, D. J. , Findlay, J. B. (1987) Homology between the pyrazine-binding protein from nasal mucosa and major urinary proteins. FEBS Letters, 212(2) pp. 225-8.

Pierpoint, W. S., Tatham, A. S. , Pappin, D. J. C. (1987) Identification of the virus-induced protein of tobacco leaves that resembles the sweet-protein thaumatin. Physiological and Molecular Plant Pathology, 31(2) pp. 291-298.

Fulcher, I. S., Pappin, D. J. , Kenny, A. J. (1986) The N-terminal amino acid sequence of pig kidney endopeptidase-24.11 shows homology with pro-sucrase-isomaltase. Biochem J, 240(1) pp. 305-8.

Findlay, J. B. , Pappin, D. J. (1986) The opsin family of proteins. Biochem J, 238(3) pp. 625-42.

Short, M. N., Turner, D. S., March, J. F., Pappin, D. J., Parente, A. , Davies, J. W. (1986) The primary structure of papaya mosaic virus coat protein. Virology, 152(1) pp. 280-3.

Fawell, S. E., Pappin, D. J., McDonald, C. J. , Higgins, S. J. (1986) Androgen-regulated proteins of rat seminal vesicle secretion constitute a structurally related family present in the copulatory plug. Mol Cell Endocrinol, 45(2-3) pp. 205-13.

Bowles, D. J., Marcus, S. E., Pappin, D. J., Findlay, J. B., Eliopoulos, E., Maycox, P. R. , Burgess, J. (1986) Posttranslational processing of concanavalin A precursors in jackbean cotyledons. J Cell Biol, 102(4) pp. 1284-97.

Cavanagh, D., Davis, P. J. , Pappin, D. J. (1986) Coronavirus IBV glycopolypeptides: locational studies using proteases and saponin, a membrane permeabilizer. Virus Res, 4(2) pp. 145-56.

Cavanagh, D., Davis, P. J., Pappin, D. J., Binns, M. M., Boursnell, M. E. , Brown, T. D. (1986) Coronavirus IBV: partial amino terminal sequencing of spike polypeptide S2 identifies the sequence Arg-Arg-Phe-Arg-Arg at the cleavage site of the spike precursor propolypeptide of IBV strains Beaudette and M41. Virus Res, 4(2) pp. 133-43.

McDonald, C., Fawell, S., Pappin, D. , Higgins, S. (1986) Electroelution of proteins from SDS gels. Trends in Genetics, 2(C) pp. 35.

Roberts, L. M., Lamb, F. I., Pappin, D. J. , Lord, J. M. (1985) The primary sequence of Ricinus communis agglutinin. Comparison with ricin. J Biol Chem, 260(29) pp. 15682-6.

Binns, M. M., Boursnell, M. E., Cavanagh, D., Pappin, D. J. , Brown, T. D. (1985) Cloning and sequencing of the gene encoding the spike protein of the coronavirus IBV. J Gen Virol, 66 ( P pp. 719-26.

McPherson, M. J., Baron, A. J., Pappin, D. J. , Wootton, J. C. (1984) Respiratory nitrate reductase of Escherichia coli. Sequence identification of the large subunit gene. FEBS Lett, 177(2) pp. 260-4.

Pappin, D. J., Findlay, J. B., Eliopoulos, E. , Brett, M. (1984) Sequence variability in the retinal-attachment domain of mammalian rhodopsins. Biochem J, 217(3) pp. 605-13.

Findlay, J. B., Barclay, P. L., Brett, M., Davison, M., Pappin, D. J. , Thompson, P. (1984) The structure of mammalian rod opsins. Vision Res, 24(11) pp. 1501-8.

Pappin, D. J. C., Eliopoulos, E., Brett, M. , Findlay, J. B. C. (1984) A structural model for ovine rhodopsin. International Journal of Biological Macromolecules, 6(2) pp. 73-76.

Findlay, J. B., Moore, A. , Pappin, D. J. (1982) Structural studies on the chromophore attachment site of rhodopsin following bleaching. FEBS Letters, 138(1) pp. 67-70.

Eliopoulos, E., Geddes, A. J., Brett, M., Pappin, D. J. C. , Findlay, J. B. (1982) A structural model for the chromophore-binding domain of ovine rhodopsin. International Journal of Biological Macromolecules, 4(5) pp. 263-268.

Findlay, J. B., Brett, M. , Pappin, D. J. (1981) Primary structure of C-terminal functional sites in ovine rhodopsin. Nature, 293(5830) pp. 314-7.

Findlay, J. B., Brett, M. , Pappin, D. J. (1981) Primary structure of C-terminal functional sites in ovine rhodopsin. Nature, 293(5830) pp. 314-7.