Additional materials of the author at
CSHL Institutional Repository

Kotagama, Kasuen, Grimme, Acadia L, Braviner, Leah, Yang, Bing, Sakhawala, Rima M, Yu, Guoyun, Benner, Lars Kristian, Joshua-Tor, Leemor , McJunkin, Katherine (2024) Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans. Nucleic Acids Research (NAR), pp. gkae170.

Kotagama, Kasuen, Grimme, Acadia L, Braviner, Leah, Yang, Bing, Sakhawala, Rima M, Yu, Guoyun, Benner, Lars Kristian, Joshua-Tor, Leemor , McJunkin, Katherine (2024) The catalytic activity of microRNA Argonautes plays a modest role in microRNA star strand destabilization in C. elegans. bioRxiv,

Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H , Tonks, Nicholas K (2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development,

Lee, Seung Cho, Adams, Dexter W, Ipsaro, Jonathan J, Cahn, Jonathan, Lynn, Jason, Kim, Hyun-Soo, Berube, Benjamin, Major, Viktoria, Calarco, Joseph P, LeBlanc, Chantal, Bhattacharjee, Sonali, Ramu, Umamaheswari, Grimanelli, Daniel, Jacob, Yannick, Voigt, Philipp, Joshua-Tor, Leemor , Martienssen, Robert A (2023) Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation. Cell, 186(19) pp. 4100-4116.e15.

Kinney, Brian, Sahu, Shubham, Stec, Natalia, Hills-Muckey, Kelly, Adams, Dexter W, Wang, Jing, Jaremko, Matt, Joshua-Tor, Leemor, Keil, Wolfgang , Hammell, Christopher M (2023) A circadian-like gene network programs the timing and dosage of heterochronic miRNA transcription during C. elegans development. Developmental Cell, pp. S1534-5807(23)00402. Elsevier BV.

Lee, Seung Cho, Adams, Dexter W, Ipsaro, Jonathan J, Cahn, Jonathan, Lynn, Jason, Kim, Hyun-Soo, Berube, Benjamin, Major, Viktoria, Calarco, Joseph P, LeBlanc, Chantal, Bhattacharjee, Sonali, Ramu, Umamaheswari, Grimanelli, Daniel, Jacob, Yannick, Voigt, Philipp, Joshua-Tor, Leemor , Martienssen, Robert A (2023) Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation. bioRxiv,

Meze, Katarina, Axhemi, Armend, Thomas, Dennis R, Doymaz, Ahmet , Joshua-Tor, Leemor (2023) A shape-shifting nuclease unravels structured RNA. Nature Structural and Molecular Biology,

Gao, Yuan, He, Xue-Yan, Wu, Xiaoli S, Huang, Yu-Han, Toneyan, Shushan, Ha, Taehoon, Ipsaro, Jonathan J, Koo, Peter K, Joshua-Tor, Leemor, Bailey, Kelly M, Egeblad, Mikala , Vakoc, Christopher R (2023) ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nature Cell Biology,

Bibel, Brianna, Elkayam, Elad, Silletti, Steve, Komives, Elizabeth A , Joshua-Tor, Leemor (2022) Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release. eLife, 11

Wu, Xiaoli S, He, Xue-Yan, Ipsaro, Jonathan J, Huang, Yu-Han, Preall, Jonathan B, Ng, David, Shue, Yan Ting, Sage, Julien, Egeblad, Mikala, Joshua-Tor, Leemor , Vakoc, Christopher R (2022) OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature,

Ipsaro, Jonathan J , Joshua-Tor, Leemor (2022) Developmental roles and molecular mechanisms of Asterix/GTSF1. Wiley Interdisciplinary Reviews: RNA, pp. e1716.

Bibel, Brianna, Elkayam, Elad, Silletti, Steve, Komives, Elizabeth , Joshua-Tor, Leemor (2022) Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release. Elife, 11(e76908)

Ipsaro, Jonathan J, O'Brien, Paul A, Bhattacharya, Shibani, Palmer, Arthur G , Joshua-Tor, Leemor (2021) Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. Cell Reports, 34(13) pp. 108914.

Meze, Katarina, Axhemi, Armend, Thomas, Dennis, Doymaz, Ahmet , Joshua-Tor, Leemor (2021) A shape-shifting nuclease unravels structured RNA. bioRxiv,

Wang, Pengfei, Liu, Lihong, Nair, Manoj S, Yin, Michael T, Luo, Yang, Wang, Qian, Yuan, Ting, Mori, Kanako, Solis, Axel Guzman, Yamashita, Masahiro, Garg, Ankur, Purpura, Lawrence J, Laracy, Justin C, Yu, Jian, Joshua-Tor, Leemor, Sodroski, Joseph, Huang, Yaoxing , Ho, David D (2020) SARS-CoV-2 neutralizing antibody responses are more robust in patients with severe disease.. Emerging Microbes and Infections, 9(1) pp. 2091-2093.

Hu, Y, Tareen, A., Sheu, Y. J., Ireland, W. T., Speck, C., Li, H., Joshua-Tor, L., Kinney, J. B. , Stillman, B. (2020) Evolution of DNA replication origin specification and gene silencing mechanisms. Nature Communications, 11(1) pp. 5175.

Jaremko, M. J., On, K. F., Thomas, D. R., Stillman, B. , Joshua-Tor, L. (2020) The dynamic nature of the human origin recognition complex revealed through five cryoEM structures. Elife, 9 pp. e58622.

Ipsaro, Jonathan J, O’Brien, Paul A, Bhattacharya, Shibani, Palmer, Arthur G , Joshua-Tor, Leemor (2020) Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons. BioRxiv,

Hu, Y, Tareen, A, Sheu, Y-J, Ireland, WT, Speck, C, Li, H, Joshua-Tor, L, Kinney, JB , Stillman, B (2020) Evolution of DNA Replication Origin Specification and Gene Silencing Mechanisms. BioRxiv,

Greider, Carol W, Sheltzer, Jason M, Cantalupo, Nancy C, Copeland, Wilbert B, Dasgupta, Nilanjana, Hopkins, Nancy, Jansen, Jaclyn M, Joshua-Tor, Leemor, McDowell, Gary S, Metcalf, Jessica L, McLaughlin, BethAnn, Olivarius, Ann, O'Shea, Erin K, Raymond, Jennifer L, Ruebain, David, Steitz, Joan A, Stillman, Bruce, Tilghman, Shirley M, Valian, Virginia, Villa-Komaroff, Lydia , Wong, Joyce Y (2019) Increasing gender diversity in the STEM research workforce.. Science, 366(6466) pp. 692-695. American Association for the Advancement of Science (AAAS).

Jung, J., Grant, T., Thomas, D. R., Diehnelt, C. W., Grigorieff, N. , Joshua-Tor, L. (2019) High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Proc Natl Acad Sci U S A, 116(26) pp. 12828-12832.

Jung, James, Grant, Timothy, Thomas, Dennis, Diehnelt, Chris, Grigorieff, Nikolaus , Joshua-Tor, Leemor (2019) High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. BioRxiv,

Stein, C. B., Genzor, P., Mitra, S., Elchert, A. R., Ipsaro, J. J., Benner, L., Sobti, S., Su, Y., Hammell, M., Joshua-Tor, L. , Haase, A. D. (2019) Decoding the 5' nucleotide bias of PIWI-interacting RNAs. Nat Commun, 10(1) pp. 828.

Ando, Y., Elkayam, E., McPherson, R. L., Dasovich, M., Cheng, S. J., Voorneveld, J., Filippov, D. V., Ong, S. E., Joshua-Tor, L. , Leung, A. K. L. (2019) ELTA: Enzymatic Labeling of Terminal ADP-Ribose. Mol Cell, 73(4) pp. 845-856 e5.

On, Kin Fan, Jaremko, Matt, Stillman, Bruce , Joshua-Tor, Leemor (2018) A structural view of the initiators for chromosome replication. Current Opinion in Structural Biology, 53 pp. 131-139.

Zhang, T., Wu, Y. C., Mullane, P., Ji, Y. J., Liu, H., He, L., Arora, A., Hwang, H. Y., Alessi, A. F., Niaki, A. G., Periz, G., Guo, L., Wang, H., Elkayam, E., Joshua-Tor, L., Myong, S., Kim, J. K., Shorter, J., Ong, S. E., Leung, A. K. L. , Wang, J. (2018) FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. Mol Cell, 69(5) pp. 787-801.e8.

Li, J., Wu, C., Wang, W., He, Y., Elkayam, E., Joshua-Tor, L. , Hammond, P. T. (2018) Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference. Proc Natl Acad Sci U S A, 115(12) pp. E2696-E2705.

Krishnan, N., Bonham, C. A., Rus, I. A., Shrestha, O. K., Gauss, C. M., Haque, A., Tocilj, A., Joshua-Tor, L. , Tonks, N. K. (2018) Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development. Nat Commun, 9(1) pp. 283.

Elkayam, Elad, Faehnle, Christopher R., Morales, Marjorie, Sun, Jingchuan, Li, Huilin , Joshua-Tor, Leemor (2017) Multivalent Recruitment of Human Argonaute by GW182. Molecular Cell, 67(4) pp. 646-658.

Faehnle, C. R., Walleshauser, J. , Joshua-Tor, L. (2017) Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat Struct Mol Biol, 24(8) pp. 658-665.

Elkayam, E., Parmar, R., Brown, C. R., Willoughby, J. L., Theile, C. S., Manoharan, M. , Joshua-Tor, L. (2017) siRNA carrying an (E)-vinylphosphonate moiety at the 5' end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. Nucleic Acids Res, 45(6) pp. 3528-3536.

Ipsaro, J. J., Shen, C., Arai, E., Xu, Y., Kinney, J. B., Joshua-Tor, L., Vakoc, C. R. , Shi, J. (2017) Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis. PLoS One, 12(2) pp. e0172177.

Tocilj, A., On, K. F., Yuan, Z., Sun, J., Elkayam, E., Li, H., Stillman, B. , Joshua-Tor, L. (2017) Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6

Shen, Chen, Ipsaro, Jonathan J, Shi, Junwei, Milazzo, Joseph P, Wang, Eric, Roe, Jae-Seok, Suzuki, Yutaka, Pappin, Darryl J, Joshua-Tor, Leemor , Vakoc, Christopher R (2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell, 60(6) pp. 847-859.

Kuhn, C. D., Wilusz, J. E., Zheng, Y., Beal, P. A. , Joshua-Tor, L. (2015) On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Febs Journal, 282(Supple) pp. 37-37.

Naguib, Adam, Bencze, Gyula, Cho, Hyejin, Zheng, Wu, Tocilj, Ante, Elkayam, Elad, Faehnle, Christopher R, Jaber, Nadia, Pratt, Christopher P, Chen, Muhan, Zong, Wei-Xing, Marks, Michael S, Joshua-Tor, Leemor, Pappin, Darryl J , Trotman, Lloyd C (2015) PTEN Functions by Recruitment to Cytoplasmic Vesicles. Molecular Cell, 58(2) pp. 255-268.

Kuhn, C. D., Wilusz, J. E., Zheng, Y., Beal, P. A. , Joshua-Tor, L. (2015) On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme. Cell, 160(4) pp. 644-658.

Ipsaro, J. J. , Joshua-Tor, L. (2015) From guide to target: molecular insights into eukaryotic RNA-interference machinery. Nat Struct Mol Biol, 22(1) pp. 20-28.

Faehnle, C. R., Walleshauser, J. , Joshua-Tor, L. (2014) Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. Nature, 514(7521) pp. 252-6.

Lee, S. J., Syed, S., Enemark, E. J., Schuck, S., Stenlund, A., Ha, T. , Joshua-Tor, L. (2014) Dynamic look at DNA unwinding by a replicative helicase. Proceedings of the National Academy of Sciences of the United States of America, 111(9) pp. E827-35.

Faehnle, C. R., Elkayam, E., Haase, A. D., Hannon, G. J. , Joshua-Tor, L. (2014) Slicer and the Argonautes. Biophysical Journal, 106(2; Sup) pp. 455A-455A.

Kuscu, C., Zaratiegui, M., Kim, H. S., Wah, D. A., Martienssen, R. A., Schalch, T. , Joshua-Tor, L. (2014) CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing. Proceedings of the National Academy of Sciences of the United States of America, 111(5) pp. 1795-1800.

Faehnle, Christopher R, Elkayam, Elad, Haase, Astrid D, Hannon, Gregory J , Joshua-Tor, Leemor (2013) The Making of a Slicer: Activation of Human Argonaute-1. Cell Reports, 3(6) pp. 1901-1909.

Clark, P., Cohen, M., Danziger, S., Eisner, L., Herz-Roiphe, R., Iwahara, Y., Kafka, O., Kiprovski, A., Koones, G., Milich, A., Mittal, S., Richardson, A., Rubenstein, J., Shapiro, J., Stern, A., Zhao, Y. G., Hackett, J. , Joshua-Tor, L. (2013) Modeling the Structure and Function of Argonaute in RNAi. Faseb Journal, 27

Naguib, A., Bencze, G., Faehnle, C. R., Schalch, T., Lazar, Z., Ruse, C. I., Joshua-Tor, L., Pappin, D. J. , Trotman, L. C. (2013) Upstream activation of PTEN. Cancer Research, 73(8 (Sup) pp. 5156.

Kuhn, C. D. , Joshua-Tor, L. (2013) Eukaryotic Argonautes come into focus. Trends in Biochemical Sciences, 38(5) pp. 263-271.

Paul, S., Kuo, A., Schalch, T., Vogel, H., Joshua-Tor, L., McCombie, W. R., Gozani, O., Hammell, M. , Mills, A. A. (2013) Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression. Cell Reports, 3(1) pp. 92-102.

Wilusz, J. E., Jnbaptiste, C. K., Lu, L. Y., Kuhn, C. D., Joshua-Tor, L. , Sharp, P. A. (2012) A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails. Genes Dev, 26(21) pp. 2392-407.

Lavy, T., Kumar, P. R., He, H. Z. , Joshua-Tor, L. (2012) The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation. Genes & Development, 26(3) pp. 294-303.

Elkayam, E., Kuhn, C. D., Tocilj, A., Haase, A. D., Greene, E. M., Hannon, G. J. , Joshua-Tor, L. (2012) The structure of human argonaute-2 in complex with miR-20a. Cell, 150(1) pp. 100-110.

Ipsaro, J. J., Haase, A. D., Knott, S. R., Joshua-Tor, L. , Hannon, G. J. (2012) The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491(7423) pp. 279-282.

Joshua-Tor, L. , Hannon, G. J. (2011) Ancestral Roles of Small RNAs: An Ago-Centric Perspective. Cold Spring Harb Perspect Biol, 3(10)

Schalch, T., Job, G., Shanker, S., Partridge, J. , Joshua-Tor, L. (2011) The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Molecular Biology of the Cell, 22

Schalch, T., Job, G., Shanker, S., Partridge, J. F. , Joshua-Tor, L. (2011) The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS. Nature Structural and Molecular Biology, 18(12) pp. 1351-1357.

Faehnle, C. R. , Joshua-Tor, L. (2010) Argonaute MID domain takes centre stage. Embo Reports, 11(8) pp. 564-5.

Schalch, T., Job, G., Noffsinger, V. J., Shanker, S., Kuscu, C., Joshua-Tor, L. , Partridge, J. F. (2009) High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin. Mol Cell, 34(1) pp. 36-46.

Kettner-Buhrow, D., Guenther, B., Kaelble, S., Joshua-Tor, L. , Kracht, M. (2009) Measurement of in vivo RISC activity using an in vitro non-radioactive RISC assay. Naunyn-Schmiedebergs Archives of Pharmacology, 379(281 Ab) pp. 59.

Enemark, E. J. , Joshua-Tor, L. (2008) On helicases and other motor proteins. Curr Opin Struct Biol, 18(2) pp. 243-257 .

Joshua-Tor, L. , Enemark, E. J. (2008) Mechanism of DNA translocation in a replicative hexameric helicase. Faseb Journal, 22

Kettner-Buhrow, D., Kaelble, S., Joshua-Tor, L. , Kracht, M. (2008) Establishment of a non-radioactive assay to measure RISC (RNA-induced silencing complex) activity in vitro. Naunyn-Schmiedebergs Archives of Pharmacology, 377(Supp 1) pp. 64-64.

Kumar, P. R., Yu, Y., Sternglanz, R., Johnston, S. A. , Joshua-Tor, L. (2008) NADP regulates the yeast GAL induction system. Science, 319(5866) pp. 1090-2.

Faehnle, Christopher R. , Joshua-Tor, Leemor (2007) Argonautes confront new small RNAs. Current Opinion in Chemical Biology, 11(5) pp. 569-577.

O'Farrell, P. A. , Joshua-Tor, L. (2007) Mutagenesis and crystallographic studies of the catalytic residues of the papain family protease bleomycin hydrolase: new insights into active-site structure. Biochem J, 401(2) pp. 421-8.

Tolia, N. H. , Joshua-Tor, L. (2007) Slicer and the Argonautes. Nature Chemical Biology, 3(1) pp. 36-43.

Irvine, D. V., Zaratiegui, Mi., Tolia, N. H., Goto, D. B., Chitwood, D. H., Vaughn, M. W., Joshua-Tor, L. , Martienssen, R. A. (2006) Argonaute slicing is required for heterochromatic silencing and spreading. Science, 313(5790) pp. 1134-7.

Enemark, E. J. , Joshua-Tor, L. (2006) Mechanism of DNA translocation in a replicative hexameric helicase. Nature, 442(7100) pp. 270-275.

Song, J. J. , Joshua-Tor, L. (2006) Argonaute and RNA--getting into the groove. Curr Opin Struct Biol, 16(1) pp. 5-11.

Tolia, N.H. , Joshua-Tor, L. (2006) Strategies for protein coexpression in Escherichia coli. Nat Methods, 3(1) pp. 55-64.

Joshua-Tor, L. (2006) The argonautes. Cold Spring Harb Symp Quant Biol, 71 pp. 67-72.

Yigit, E., Batista, P. J., Bei, Y., Pang, K. M., Chen, C. C. G., Tolia, N. H., Joshua-Tor, L., Mitani, S., Simard, M. J. , Mello, C. C. (2006) Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi. Cell, 127(4) pp. 747-757.

Tolia, N. H., Enemark, E. J., Sim, B. K. , Joshua-Tor, L. (2005) Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell, 122(2) pp. 183-93.

Rivas, Fabiola V., Tolia, Nirja H., Song, Ji-Joon, Aragon, Juan P., Liu, Jidong, Hannon, Gregory J. , Joshua-Tor, Leemor (2005) Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol, 12(4) pp. 340-9.

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L. , Hannon, G. J. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science, 305(5689) pp. 1437-41.

Song, J. J., Smith, S. K., Hannon, G. J. , Joshua-Tor, L. (2004) Crystal structure of argonaute and its implications for RISC slicer activity. Science, 305(5689) pp. 1434-1437.

Joshua-Tor, L. (2004) siRNAs at RISC. Structure, 12(7) pp. 1120-1122.

Auster, A. S. , Joshua-Tor, L. (2004) The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J Biol Chem, 279(5) pp. 3733-42.

Song, J. J., Liu, J., Tolia, N. H., Schneiderman, J., Smith, S. K., Martienssen, R. A., Hannon, G. J. , Joshua-Tor, L. (2003) The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol, 10(12) pp. 1026-32.

Enemark, E. J., Stenlund, A. , Joshua-Tor, L. (2002) Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex. Embo Journal, 21(6) pp. 1487-1496.

Messick, T. E., Chmiel, N. H., Golinelli, M. P., Langer, M. R., Joshua-Tor, L. , David, S. S. (2002) Noncysteinyl coordination to the [4Fe-4S](2+) cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster. Biochemistry, 41(12) pp. 3931-3942.

van Aalten, D. M., Haker, A., Hendriks, J., Hellingwerf, K. J., Joshua-Tor, L. , Crielaard, W. (2002) Engineering photocycle dynamics. Crystal structures and kinetics of three photoactive yellow protein hinge-bending mutants. J Biol Chem, 277(8) pp. 6463-8.

Van Aalten, D. M. F., Crielaard, W., Hellingwerf, K. J. , Joshua-Tor, L. (2002) Structure of the photoactive yellow protein reconstituted with caffeic acid at 1.16 Å resolution. Acta Crystallographica Section D: Biological Crystallography, 58(4) pp. 585-590.

Russell, S. J., Gonzalez, F., Joshua-Tor, L. , Johnston, S. A. (2001) Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases. Chemistry & Biology, 8(10) pp. 941-950.

David, S. S., Golinelli, M. P., Chmiel, N. H., Langer, M. R., Chepanoske, C. L., Messick, T. R. , Joshua-Tor, L. (2001) Participation of the iron-sulfur cluster loop (FCL) motif of the adenine glycosylase MutY in DNA damage recognition and repair. Abstracts of Papers of the American Chemical Society, 222 pp. U578-U578.

van Aalten, D. M. F., Chong, C. R. , Joshua-Tor, L. (2000) Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes. Biochemistry, 39(33) pp. 10082-10089.

Enemark, E. J., Chen, G., Vaughn, D. E., Stenlund, A. , Joshua-Tor, L. (2000) Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus. Molecular Cell, 6(1) pp. 149-158.

Van Aalten, D. M. F., Crielaard, W., Hellingwerf, K. J. , Joshua-Tor, L. (2000) Conformational substates in different crystal forms of the photoactive yellow protein - Correlation with theoretical and experimental flexibility. Protein Science, 9(1) pp. 64-72.

van Aalten, D. M., Erlanson, D. A., Verdine, G. L. , Joshua-Tor, L. (1999) A structural snapshot of base-pair opening in DNA. Proc Natl Acad Sci U S A, 96(21) pp. 11809-14.

O'Farrell, P. A., Gonzalez, F., Zheng, W., Johnston, S. A. , Joshua-Tor, L. (1999) Crystal structure of human bleomycin hydrolase, a self-compartmentalizing cysteine protease. Structure, 7(6) pp. 619-27.

Vaughn, D. E., Rodriguez, J., Lazebnik, Y. , Joshua-Tor, L. (1999) Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling. Journal of Molecular Biology, 293(3) pp. 439-447.

Zheng, W., Johnston, S. A. , Joshua-Tor, L. (1998) The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell, 93(1) pp. 103-9.

Van Aalten, D. M. F., Grotewold, E. , Joshua-Tor, L. (1998) Essential dynamics from NMR clusters: Dynamic properties of the Myb DNA-binding domain and a hinge-bending enhancing variant. Methods, 14(3) pp. 318-328.

Schlessman, J. L., Woo, D., Joshua-Tor, L., Howard, J. B. , Rees, D. C. (1998) Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum. Journal of Molecular Biology, 280(4) pp. 669-685.

Zheng, W., Joshua-Tor, L. , Johnston, S. A. (1997) Bleomycin hydrolase, a new family of cysteine peptidases reveal a novel mechanism of peptide degradation. Faseb Journal, 11(9) pp. A1395-A1395.

Joshua-Tor, L., Xu, H., Johnston, S. , Rees, D. (1995) Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science, 269(5226) pp. 945-950.

Joshua-Tor, L. , Sussman, J. L. (1993) The Coming of Age of DNA Crystallography. Current Opinion in Structural Biology, 3(3) pp. 323-335.

Blake, P. R., Day, M. W., Hsu, B. T., Joshua-Tor, L., Park, J. B., Hare, D. R., Adams, M. W., Rees, D. C. , Summers, M. F. (1992) Comparison of the X-ray structure of native rubredoxin from Pyrococcus furiosus with the NMR structure of the zinc-substituted protein. Protein Sci, 1(11) pp. 1522-5.

Joshua-Tor, L., Frolow, F., Appella, E., Hope, H., Rabinovich, D. , Sussman, J. L. (1992) Three-dimensional structures of bulge-containing DNA fragments. J Mol Biol, 225(2) pp. 397-431.

Berman, H. M., Sussman, J. L., Joshua-Tor, L., Revich, G. G. , Ripley, L. S. (1992) A structural model for sequence-specific proflavin-DNA interactions during in vitro frameshift mutagenesis. Journal of Biomolecular Structure and Dynamics, 10(2) pp. 317-331.

Day, M. W., Hsu, B. T., Joshua-Tor, L., Park, J. B., Zhou, Z. H., Adams, M. W. W. , Rees, D. C. (1992) X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Science, 1(11) pp. 1494-1507.

Joshua-Tor, L., Rabinovich, D., Hope, H., Frolow, F., Appella, E. , Sussman, J. L. (1988) The three-dimensional structure of a DNA duplex containing looped-out bases. Nature, 334(6177) pp. 82-4.