Jacobsen, M. F., Moses, J. E., Adlington, R. M., Baldwin, J. E. (February 2005) A short total synthesis of aureothin and N-acetylaureothamine. Org Lett, 7 (4). pp. 641-4. ISSN 1523-7060 (Print)1523-7052
DOI: 10.1021/ol047594l
Abstract
The total synthesis of the nitrophenyl pyrones, (+/-)-aureothin and (+/-)-N-acetylaureothamine, starting from known 2-ethyl-6-methoxy-3,5-dimethyl-4H-pyran-4-one are described. The key steps involved in the synthesis are the construction of the tetrahydrofuran motif using a palladium-catalyzed cycloaddition and the ruthenium-catalyzed cross-metathesis reaction of an alkenyl boronic ester. [reaction: see text]
| Item Type: | Paper |
|---|---|
| Additional Information: | Organic letters |
| Uncontrolled Keywords: | Acetylation Amines/chemical synthesis Chromones/chemical synthesis/chemistry Indicators and Reagents Models, Molecular Stereoisomerism |
| Communities: | CSHL labs > Moses lab |
| Depositing User: | Matthew Dunn |
| Date: | 17 February 2005 |
| Date Deposited: | 19 Apr 2021 21:28 |
| Last Modified: | 19 Apr 2021 21:28 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/39527 |
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