A Pliable ERα Cistrome Evades Therapy

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Wu, X.S., Vakoc, C. R. (May 2020) A Pliable ERα Cistrome Evades Therapy. Nat Cell Biol, 22 (6). pp. 619-620. ISSN 1465-7392

URL: https://pubmed.ncbi.nlm.nih.gov/32424274/

DOI: 10.1038/s41556-020-0528-6

Abstract

The transcription factor oestrogen receptor alpha (ERα) has long been targeted for therapeutic benefit in cancer, but drug resistance can emerge through a multitude of mechanisms. A study now reveals how the ERα cistrome can become reprogrammed to confer resistance to tamoxifen in breast cancer.

Item Type:	Paper
CSHL Authors:	Vakoc, Christopher R. Wu, Xiaoli
Communities:	CSHL labs > Vakoc lab
Depositing User:	Adrian Gomez
Date:	18 May 2020
Date Deposited:	21 May 2020 17:00
Last Modified:	06 Jul 2020 15:05
Related URLs:	Publisher
URI:	https://repository.cshl.edu/id/eprint/39470

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