A Pliable ERα Cistrome Evades Therapy

Wu, X.S., Vakoc, C. R. (May 2020) A Pliable ERα Cistrome Evades Therapy. Nat Cell Biol, 22 (6). pp. 619-620. ISSN 1465-7392

URL: https://pubmed.ncbi.nlm.nih.gov/32424274/
DOI: 10.1038/s41556-020-0528-6


The transcription factor oestrogen receptor alpha (ERα) has long been targeted for therapeutic benefit in cancer, but drug resistance can emerge through a multitude of mechanisms. A study now reveals how the ERα cistrome can become reprogrammed to confer resistance to tamoxifen in breast cancer.

Item Type: Paper
CSHL Authors:
Communities: CSHL labs > Vakoc lab
Depositing User: Adrian Gomez
Date: 18 May 2020
Date Deposited: 21 May 2020 17:00
Last Modified: 06 Jul 2020 15:05
Related URLs:
URI: https://repository.cshl.edu/id/eprint/39470

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