CORE: A Software Tool for Delineating Regions of Recurrent DNA Copy Number Alteration in Cancer

Sun, G., Krasnitz, A. (2019) CORE: A Software Tool for Delineating Regions of Recurrent DNA Copy Number Alteration in Cancer. Methods Mol Biol, 1878. pp. 85-93. ISSN 1064-3745

URL: https://www.ncbi.nlm.nih.gov/pubmed/30378070
DOI: 10.1007/978-1-4939-8868-6_4

Abstract

Collections of genomic intervals are a common data type across many areas of computational biology. In cancer genomics, in particular, the intervals often represent regions with altered DNA copy number, and their collections exhibit recurrent features, characteristic of a given cancer type. Cores of Recurrent Events (CORE) is a versatile computational tool for identification of such recurrent features. Here we provide practical guidance for the use of CORE, implemented as an eponymous R package.

Item Type: Paper
Subjects: diseases & disorders > cancer
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes > comparative genomics
bioinformatics > genomics and proteomics > computers > computer software
CSHL Authors:
Communities: CSHL labs > Krasnitz lab
Depositing User: Matthew Dunn
Date: 2019
Date Deposited: 12 Nov 2018 21:48
Last Modified: 12 Nov 2018 21:48
Related URLs:
URI: http://repository.cshl.edu/id/eprint/37359

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