Cellular response to insulin in suprarenals of pigeons

Riddle, Oscar, Miller, Richard A. (1941) Cellular response to insulin in suprarenals of pigeons. Proceedings of the Society for Experimental Biology and Medicine, 47. pp. 449-453.

URL: http://journals.sagepub.com/doi/pdf/10.3181/003797...

Abstract

In tests made on 41 normal young White Carneau pigeons daily injections of 1-60 units of insulin during 10 hours to 10 days enlarged the adrenals, produced mitosis and cellular activity. These cytological effects were more pronounced in cortical cells than in medullary cells. Wholly comparable effects were produced in the adrenals of 16 additional birds previously deprived of their anterior pituitary glands. The cytological changes in the cortex following insulin are identical with those induced by adrenotrophic pituitary extracts. Food consumption of the test animals and of 73 controls was regulated at different and definite levels.

Item Type: Paper
Subjects: organism description > animal > bird
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > insulin receptor
CSHL Authors:
Communities: The Carnegie Institution Department of Genetics
Depositing User: Elizabeth Pessala
Date: 1941
Date Deposited: 27 Feb 2018 15:23
Last Modified: 27 Feb 2018 15:23
URI: http://repository.cshl.edu/id/eprint/36153

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