The central amygdala controls learning in the lateral amygdala

Yu, K., Ahrens, S., Zhang, X., Schiff, H., Ramakrishnan, C., Fenno, L., Deisseroth, K., Zhao, F., Luo, M. H., Gong, L., He, M., Zhou, P., Paninski, L., Li, B. (December 2017) The central amygdala controls learning in the lateral amygdala. Nat Neurosci, 20 (12). pp. 1680-1685. ISSN 1097-6256

URL: https://www.ncbi.nlm.nih.gov/pubmed/29184202
DOI: 10.1038/s41593-017-0009-9

Abstract

Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a learning process remains unclear. Here we show that PKC-delta-expressing central amygdala neurons are essential for the synaptic plasticity underlying learning in the lateral amygdala, as they convey information about the unconditioned stimulus to lateral amygdala neurons during fear conditioning.

Item Type: Paper
Subjects: organs, tissues, organelles, cell types and functions > tissues types and functions > amygdala
organism description > animal behavior > learning
CSHL Authors:
Communities: CSHL labs > Li lab
Depositing User: Matt Covey
Date: December 2017
Date Deposited: 08 Dec 2017 17:52
Last Modified: 08 Dec 2017 17:52
Related URLs:
URI: http://repository.cshl.edu/id/eprint/35706

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving