Vass, K., Berger, M. L., Nowak, T. S., Welch, W. J., Lassmann, H. (May 1989) Induction of Stress Protein Hsp70 in Nerve-Cells after Status Epilepticus in the Rat. Neuroscience Letters, 100 (1-3). pp. 259-264. ISSN 0304-3940
Abstract
The accumulation of the stress protein HSP70 was found to be an excellent marker for prolonged seizure related metabolic activity of neurons. After kainic acid (KA) induced status epilepticus we observed HSP70 immunoreactivity in the hippocampal CA4 and CA1 sectors, the subiculum, the basolateral and the lateral nuclei of the amygdala, the mediodorsal nucleus of the thalamus, the caudal part of the striatum, the claustrum and in neurons of certain neocortical areas. HSP70-positive nerve cells appeared normal in conventional histological stains. Conversely, degenerating neurons (e.g. in the hippocampal CA3 sector) remained unlabeled.
| Item Type: | Paper |
|---|---|
| Subjects: | diseases & disorders > nervous system diseases and disorders > epilepsy organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organs, tissues, organelles, cell types and functions > cell types and functions > cell types > neurons organism description > animal > mammal > rodent > rat organism description > animal > mammal > rodent > rat |
| CSHL Authors: | |
| Communities: | CSHL labs |
| Depositing User: | Gail Sherman |
| Date: | May 1989 |
| Date Deposited: | 23 Jun 2017 15:17 |
| Last Modified: | 23 Jun 2017 15:17 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/34914 |
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