The rate of escape of hemoglobin from the hemolyzed red corpuscle

Fricke, Hugo (September 1934) The rate of escape of hemoglobin from the hemolyzed red corpuscle. J Gen Physiol., 18 (1). pp. 103-107.

URL: https://www.ncbi.nlm.nih.gov/pubmed/19872819

Abstract

A theoretical treatment is given of the rate of escape of hemoglobin from the hemolyzed red corpuscle. For complete permeability of the surface, as may perhaps be produced by strong lysins, the time taken for the hemoglobin to decrease to 10 per cent of its original concentration is calculated to be 0.16 seconds (for the human cell). For dilute saponin, giving complete lysis of human cells in 3 minutes, Ponder found a time of escape of 4 seconds, from which the permeability of the membrane to the pigment is calculated to be µH = 5 x 10–5 cm./sec.

Item Type: Paper
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > red blood cells
Communities: The Biological Laboratory
Depositing User: Elizabeth Pessala
Date: 20 September 1934
Date Deposited: 19 May 2017 15:10
Last Modified: 19 May 2017 15:10
PMCID: PMC2141332
URI: http://repository.cshl.edu/id/eprint/34762

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