Controlling elements and the gene

McClintock, B. (1956) Controlling elements and the gene. Cold Spring Harb Symp Quant Biol, 21. pp. 197-216. ISSN 0091-7451 (Print)0091-7451 (Linking)

URL: https://www.ncbi.nlm.nih.gov/pubmed/13433592
DOI: 10.1101/SQB.1956.021.01.017

Abstract

In a recent brief review (McClintock, 1956), a description was given of types of elements carried in the maize chromosomes that serve to control gene action and to induce, at the site of the gene, heritable modifications affecting this action. These elements were initially discovered because they do not remain at one position in the chromosome complement. They can appear at new locations and disappear from previously determined locations. The presence of one such element at or near the locus of a known gene may affect the action of this gene. In so doing, it need not alter the action potentials of the genic substances at the locus. Therefore, these elements were called controlling elements. It was also shown that controlling elements fall into groups, the members of each operating as an integrated system in the control of gene action.

Item Type: Paper
Uncontrolled Keywords: *Chromosomes Humans
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome
CSHL Authors:
Communities: CSHL labs > McClintock lab
Depositing User: Matt Covey
Date: 1956
Date Deposited: 25 Apr 2017 16:36
Last Modified: 25 Apr 2017 16:36
Related URLs:
URI: http://repository.cshl.edu/id/eprint/34619

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