Reproduction of bacteriophage

Hershey, Alfred Day (1952) Reproduction of bacteriophage. International Review of Cytology, 1. pp. 119-134.

URL: http://www.sciencedirect.com/science/article/pii/S...
DOI: 10.1016/S0074-7696(08)60008-X

Abstract

This chapter focuses on the reproduction of bacteriophage. The most numerous classes of coliphages, brought together on the basis of antigenic relatedness and morphologic identity, is the one containing T2 and T4. These are among the largest of the viruses. They are tadpole-shaped particles measuring about 0.1 micron in diameter. The particles are subject to osmotic shock and presumably possess some sort of membrane. The sequence of events occurring during the intracellular existence of phages, such as T2, is summarized in the chapter. Soon after entering the cell, the resting phage is transformed into vegetative phage. These two forms of virus have no known attribute in common except genetic continuity. Each has one known capacity that is unique; resting phage can infect bacteria, vegetative phage can multiply intracellularly. There is a marked difference between the two forms in sensitivity to ultraviolet light. Multiplication begins some time before the midpoint of the latent period and may be confined to the second quarter. Beginning at the midpoint of the latent period, the vegetative progeny are converted to the resting form at a linear rate. Genetic interaction immediately precedes or is part of this process.

Item Type: Paper
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
CSHL Authors:
Communities: The Carnegie Institution Department of Genetics
Depositing User: Matt Covey
Date: 1952
Date Deposited: 18 Apr 2017 20:14
Last Modified: 18 Apr 2017 20:14
URI: http://repository.cshl.edu/id/eprint/34528

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving