Bacteriophage Mu-induced modification of DNA is dependent upon a host function

Khatoon, H., Bukhari, A. I. (October 1978) Bacteriophage Mu-induced modification of DNA is dependent upon a host function. J Bacteriol, 136 (1). pp. 423-8. ISSN 0021-9193 (Print)0021-9193 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/361700

Abstract

The DNA of bacteriophage Mu, extracted from induced lysates, is partially resistant to digestion by the endonuclease BalI. This modification of DNA is controlled by the Mu modification function (mom), which acts in conjunction with the dam (DNA-adenine methylation) function of Escherichia coli. Since the BalI recognition site is apparently different from the dam recognition site, these results imply that either the specificity of the dam function is changed by the mom function or the mom function requires the dam function for its activity.

Item Type: Paper
Uncontrolled Keywords: Coliphages/genetics/*metabolism DNA Restriction Enzymes DNA, Viral/*metabolism Escherichia coli/genetics/*metabolism Genes Methylation Mutation
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > bacteriophage
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: October 1978
Date Deposited: 12 Dec 2016 19:53
Last Modified: 12 Dec 2016 19:53
PMCID: PMC218675
Related URLs:
URI: http://repository.cshl.edu/id/eprint/33319

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