Adenovirus DNA-Replication in Soluble Extracts of Infected Cell-Nuclei

Horwitz, M. S., Kaplan, L. M., Abboud, M., Maritato, J., Chow, L. T., Broker, T. R. (1979) Adenovirus DNA-Replication in Soluble Extracts of Infected Cell-Nuclei. Cold Spring Harb Symp Quant Biol, 43. pp. 769-780. ISSN 0091-7451

URL: http://www.ncbi.nlm.nih.gov/pubmed/226320
DOI: 10.1101/SQB.1979.043.01.084

Abstract

Synthesis of viral DNA after infection of prokaryotic and eukaryotic cells has been studied to understand the replication of the viral genome itself, as well as to serve as a substrate for the analysis of components necessary for host-chromosomal replication (Kaufmann et al. 1977; Kornberg; Sumida-Yasumoto et al.; Hillenbrand et al.; Liu et al.; all this volume). Viral systems have been essential because the physical and enzymatic studies used to characterize the replication reaction are considerably more difficult on the large host DNA molecules. These models have been particularly useful in the study of the molecular mechanisms of prokaryotic DNA replication because many of the smaller phages require host-coded gene products for replication (Wickner and Hurwitz, 1975; Bouché et al. 1975; Sumida-Yasumoto et al.; Meyer et al.; both this volume).

Item Type: Paper
Subjects: organism description > virus > adenovirus
organs, tissues, organelles, cell types and functions > organelles, types and functions > nucleus
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: 1979
Date Deposited: 12 Dec 2016 20:06
Last Modified: 12 Dec 2016 20:06
Related URLs:
URI: http://repository.cshl.edu/id/eprint/33308

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