The isolation of defective variants of simian virus 40 whose genomes contain sequences derived from adenovirus 2 DNA

Sambrook, J. (1978) The isolation of defective variants of simian virus 40 whose genomes contain sequences derived from adenovirus 2 DNA. J Gen Virol, 38 (2). pp. 313-27. ISSN 0022-1317 (Print)0022-1317 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/203654
DOI: 10.1099/0022-1317-38-2-313

Abstract

A new set of hybrid viruses has been isolated whose closed circular genomes 5 to 6 kB in size, contain DNA sequences derived in part from adenoviruses 2 and in part from SV40. The structure of these genomes is complex, but in the simplest case, analyses by restriction endonuclease digestion and hybridization indicate that the adenovirus 2 DNA is present as a continuous block, of maximum size 2.8 kB. Different hybrids contain sequences derived from different segments of the adenovirus 2 genome.

Item Type: Paper
Uncontrolled Keywords: Adenoviridae/*genetics Adenoviruses, Simian/*genetics Base Sequence *DNA, Viral Defective Viruses/*isolation & purification Genetic Complementation Test Genetic Variation *Nucleic Acid Hybridization Simian virus 40/*genetics
Subjects: organism description > virus > adenovirus
organism description > virus > SV40
CSHL Authors:
Depositing User: Matt Covey
Date Deposited: 12 Dec 2016 21:43
Last Modified: 12 Dec 2016 21:43
Related URLs:
URI: http://repository.cshl.edu/id/eprint/33298

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