Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits

Je, B. I., Gruel, J., Lee, Y. K., Bommert, P., Arevalo, E. D., Eveland, A. L., Wu, Q., Goldshmidt, A., Meeley, R., Bartlett, M., Komatsu, M., Sakai, H., Jonsson, H., Jackson, D. (July 2016) Signaling from maize organ primordia via FASCIATED EAR3 regulates stem cell proliferation and yield traits. Nat Genet, 48 (7). pp. 785-791. ISSN 1546-1718 (Electronic)1061-4036 (Linking) (Public Dataset)

URL: http://www.ncbi.nlm.nih.gov/pubmed/27182966
DOI: 10.1038/ng.3567

Abstract

Shoot apical meristems are stem cell niches that balance proliferation with the incorporation of daughter cells into organ primordia. This balance is maintained by CLAVATA-WUSCHEL feedback signaling between the stem cells at the tip of the meristem and the underlying organizing center. Signals that provide feedback from organ primordia to control the stem cell niche in plants have also been hypothesized, but their identities are unknown. Here we report FASCIATED EAR3 (FEA3), a leucine-rich-repeat receptor that functions in stem cell control and responds to a CLAVATA3/ESR-related (CLE) peptide expressed in organ primordia. We modeled our results to propose a regulatory system that transmits signals from differentiating cells in organ primordia back to the stem cell niche and that appears to function broadly in the plant kingdom. Furthermore, we demonstrate an application of this new signaling feedback, by showing that weak alleles of fea3 enhance hybrid maize yield traits.

Item Type: Paper
Subjects: organism description > plant > maize
organs, tissues, organelles, cell types and functions > tissues types and functions > apical meristem
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organism description > plant
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > stem cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > stem cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > stem cells
CSHL Authors:
Communities: CSHL labs > Jackson lab
Depositing User: Matt Covey
Date: July 2016
Date Deposited: 24 May 2016 19:51
Last Modified: 07 Sep 2017 14:35
Related URLs:
Dataset ID:
URI: http://repository.cshl.edu/id/eprint/32809

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving