Rapid rise in cyclic GMP accompanies catecholamine secretion in suspensions of isolated adrenal chromaffin cells

Schneider, A. S., Cline, H. T., Lemaire, S. (April 1979) Rapid rise in cyclic GMP accompanies catecholamine secretion in suspensions of isolated adrenal chromaffin cells. Life Sci, 24 (15). pp. 1389-94. ISSN 0024-3205 (Print)0024-3205 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/225615
DOI: 10.1016/0024-3205(79)90009-2

Abstract

Acetylcholine stimulates a five-fold increase in cyclic GMP within seconds of addition to suspensions of isolated adrenal chromaffin cells. The rapid kinetics and dose-response curve for cyclic GMP accumulation are compared with corresponding results for catecholamine secretion and a possible role of cyclic GMP in stimulus-secretion coupling is considered.

Item Type: Paper
Uncontrolled Keywords: Acetylcholine/pharmacology Adrenal Medulla/cytology/*metabolism/secretion Animals Catecholamines/*secretion Cattle Chromaffin System/cytology/*metabolism/secretion Cyclic GMP/*metabolism In Vitro Techniques Kinetics Time Factors
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > transcription factor > Cyclic GMP
CSHL Authors:
Communities: CSHL labs > Cline lab
Depositing User: Matt Covey
Date: 9 April 1979
Date Deposited: 06 May 2016 19:16
Last Modified: 06 May 2016 19:16
Related URLs:
URI: http://repository.cshl.edu/id/eprint/32710

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