Single-cell molecular profiling of fluid biopsies of epithelial ovarian cancer

Velasco, C. R., Stepansky, A., Dago, A., Carlson, A., Kolatkar, A., Kendall, J., Hicks, J., Kuhn, P. (August 2015) Single-cell molecular profiling of fluid biopsies of epithelial ovarian cancer. Clinical Cancer Research, 21. ISSN 1078-0432

URL: http://clincancerres.aacrjournals.org/content/21/1...
DOI: 10.1158/1557-3265.ovcasymp14-poster-tech-1114

Abstract

The immediate goal of this project is to identify rare circulating tumor cells (CTC) in the bloodstream of epithelial ovarian cancer (EOC) patients and to apply high content, single cell assays that will yield information on morphology, protein expression and genomic structure. The ultimate goal is to develop a minimally invasive “fluid biopsy” for ovarian patients that can provide detailed information on the patient’s response to therapy, early warnings of potential resistance or relapse, and genetic predictors for the most appropriate therapy.

Item Type: Paper
Additional Information: Meeting Abstract
Subjects: bioinformatics
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > epithelial cell

Publication Type > Meeting Abstract
diseases & disorders > cancer > cancer types > ovarian cancer
Investigative techniques and equipment > assays > Single cell sequencing
CSHL Authors:
Communities: CSHL labs > Hicks lab
CSHL labs > Wigler lab
Depositing User: Matt Covey
Date: August 2015
Date Deposited: 27 Oct 2015 19:51
Last Modified: 06 Feb 2018 15:52
URI: http://repository.cshl.edu/id/eprint/31951

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving