Paired-like repression/activation in pituitary development

Olson, L. E., Dasen, J. S., Ju, B. G., Tollkuhn, J., Rosenfeld, M. G. (2003) Paired-like repression/activation in pituitary development. Recent Prog Horm Res, 58. pp. 249-61. ISSN 0079-9963 (Print)0079-9963 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/12795422

Abstract

Pituitary gland development is controlled by signals that guide expression of specific combinations of transcription factors that dictate serial determination and differentiation events. One class of factors is paired-like homeodomain factors. Two that have been investigated are the repressor Hex1/Rpx and activator prophet of Pit-1 (Prop-1), which exert selective roles during pituitary development. The opposing actions of these factors provide one aspect of pituitary organogenesis.

Item Type: Paper
Uncontrolled Keywords: Animals Basic Helix-Loop-Helix Transcription Factors Homeodomain Proteins/genetics/ physiology Humans Mutation Organogenesis Pituitary Gland/embryology/ growth & development
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > homeodomain protein
organs, tissues, organelles, cell types and functions > tissues types and functions > suprachiasmatic nucleus > hypothalamus
organs, tissues, organelles, cell types and functions > tissues types and functions > hypothalamus

organs, tissues, organelles, cell types and functions > tissues types and functions > pituitary gland
CSHL Authors:
Communities: CSHL labs > Tollkuhn lab
Depositing User: Matt Covey
Date Deposited: 23 Jul 2015 19:02
Last Modified: 23 Jul 2015 19:02
URI: http://repository.cshl.edu/id/eprint/31661

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