Assembly of nucleosomes: do multiple assembly factors mean multiple mechanisms?

Kaufman, P. D., Botchan, M. R. (April 1994) Assembly of nucleosomes: do multiple assembly factors mean multiple mechanisms? Curr Opin Genet Dev, 4 (2). pp. 229-35. ISSN 0959-437X (Print)

URL: http://www.ncbi.nlm.nih.gov/pubmed/8032200
DOI: 10.1016/S0959-437X(05)80049-8

Abstract

In eukaryotic cells, transcription and DNA replication occur on DNA templates associated with chromatin proteins, most notably histone octamers. Protein factors that can assemble these units have been isolated from many sources. In particular, one factor from human cells is associated with ongoing DNA synthesis; other known assembly factors are not obligately coupled to the replication process. The wide variety of histone chaperones suggests that multiple pathways for the remodeling of chromatin structure have evolved.

Item Type: Paper
Uncontrolled Keywords: Animals Chromosomes DNA Replication Humans Nuclear Proteins/physiology Nucleosomes Research Support, Non-U.S. Gov't
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA replication
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > nucleosome
CSHL Authors:
Communities: CSHL labs > Stillman lab
Depositing User: Matt Covey
Date: April 1994
Date Deposited: 03 Aug 2015 18:43
Last Modified: 03 Aug 2015 18:43
Related URLs:
URI: http://repository.cshl.edu/id/eprint/31441

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving