Biochemical and genetic dissection of mitotic chromosome condensation

Hirano, T. (1995) Biochemical and genetic dissection of mitotic chromosome condensation. Trends Biochem Sci, 20 (9). pp. 357-61. ISSN 0968-0004 (Print)

URL: http://www.ncbi.nlm.nih.gov/pubmed/7482703
DOI: 10.1016/S0968-0004(00)89076-3

Abstract

The molecular mechanisms responsible for mitotic chromosome condensation are unknown. Two independent approaches, biochemical studies in vertebrate cells and genetic analyses in yeasts, have converged recently, leading to the identification of a family of putative ATPases that play a fundamental role in this process. Further characterization of these proteins promises to uncover a highly dynamic aspect of mitotic chromosome architecture.

Item Type: Paper
Uncontrolled Keywords: Adenosinetriphosphatase/physiology Animals Chromosomes/ chemistry/ genetics Interphase Mitosis Nuclear Proteins/physiology
Subjects: organism description > animal
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome

organs, tissues, organelles, cell types and functions > organelles, types and functions > mitosis
CSHL Authors:
Communities: CSHL labs > Hirano lab
Depositing User: Jessica Koos
Date Deposited: 12 Aug 2014 15:25
Last Modified: 12 Aug 2014 15:25
Related URLs:
URI: http://repository.cshl.edu/id/eprint/30607

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