Out-of body experiences: cell-free cell death

Hengartner, M. O. (June 1995) Out-of body experiences: cell-free cell death. Bioessays, 17 (6). pp. 549-52. ISSN 0265-9247 (Print)

URL: http://www.ncbi.nlm.nih.gov/pubmed/7575497

Abstract

Apoptosis (programmed cell death) is an evolutionarily conserved cellular process, important for development and homeostasis. Most apoptotic cells share a common set of morphological and physiological characteristics that distinguish them from necrotic deaths. While genetic studies have indicated that these characteristic changes result from the activation of an endogenous 'suicide program', little is known about the nature of this program and the molecular events underlying these changes. Two recent papers describing cell-free extracts that reproduce several of the characteristic changes observed in apoptotic cells promise to make these phenomena accessible to biochemical analysis.

Item Type: Paper
Uncontrolled Keywords: Animals Apoptosis Cell-Free System Comparative Study Female Homeostasis Mammals Necrosis Oocytes/physiology Research Support, Non-U.S. Gov't Xenopus
Subjects: organism description > animal
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > apoptosis
organism description > animal > gender > female
organism description > animal > mammal
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > necrosis
organism description > animal > Frog > xenopus
CSHL Authors:
Communities: CSHL labs > Hengartner lab
Depositing User: Jessica Koos
Date: June 1995
Date Deposited: 11 Aug 2014 16:00
Last Modified: 11 Aug 2014 16:00
URI: http://repository.cshl.edu/id/eprint/30602

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving