Diagnosis of human heritable defects by recombinant DNA methods

Caskey, C. T., Gibbs, R. A., Witkowski, J. A., Hejtmancik, J. F. (June 1988) Diagnosis of human heritable defects by recombinant DNA methods. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 319 (1194). pp. 353-60. ISSN 0962-8436 (Print)0962-8436

URL: http://www.ncbi.nlm.nih.gov/pubmed/2900528
DOI: 10.1098/rstb.1988.0056

Abstract

Recombinant DNA methods provide highly sensitive means for the detection of DNA alterations that lead to human disease mutations. In this paper I shall illustrate the approaches currently available and discuss new technologies that show promise of replacing the present methods. Medical diagnosis by means of recombinant DNA methods has an expanding role in clinical medicine.

Item Type: Paper
Uncontrolled Keywords: *DNA, Recombinant Female Genetic Diseases, Inborn/*diagnosis Genetic Engineering/methods *Genetic Techniques Humans *Mutation Pregnancy Prenatal Diagnosis
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
Investigative techniques and equipment
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > recombination
CSHL Authors:
Communities: Banbury Center
Depositing User: Matt Covey
Date: 15 June 1988
Date Deposited: 01 Dec 2014 20:42
Last Modified: 01 Dec 2014 20:42
Related URLs:
URI: http://repository.cshl.edu/id/eprint/30410

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving