Molecular Biology of the Gene

Watson, J.D., Baker, T., Bell, S., Gann, A., Levine, M., Losick, R. (2003) Molecular Biology of the Gene. Pearson/Benjamin Cummings. ISBN 9780805346350

URL: http://www.pearsonhighered.com/educator/academic/p...

Abstract

The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson and Crick's paper on the structure of the DNA double-helix. Though completely updated, the new edition retains the distinctive character of earlier editions that made it the most widely used book in molecular biology. Twenty-one concise chapters, co-authored by five highly respected molecular biologists, provide current, authoritative coverage of a fast-changing discipline. The completely new art is printed in full color for the first time. Divided into five parts, the first (Chemistry and Genetics) begins with an overview of molecular biology, placing the discipline in historical context and introducing the basic chemical concepts that underpin our description of molecular biology today. The second and third parts (Maintenance of the Genome and Expression of the Genome) form the heart of the book, describing in detail the basic mechanisms of DNA replication, transcription and translation. The fourth part of the book (Regulation) deals with how gene expression is regulated - from the examination of basic mechanisms that regulate gene expression in bacterial and eukaryotic systems, to a description of how regulation of gene expression lies at the heart of the process of development. Recent findings from sequencing whole genomes of several animals have revealed that they all share essentially the same genes. The last chapter in the regulation section looks at how changes in gene regulation can account for how different animals can be made up of the same genes. The final part of the book (Methods) deals with the techniques and methods used in molecular biology.

Item Type: Book
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
manuals and technical reports
CSHL Authors:
Communities: CSHL labs
Watson School
Depositing User: Matt Covey
Date: 2003
Date Deposited: 23 Jun 2014 19:31
Last Modified: 23 Jun 2014 19:31
URI: http://repository.cshl.edu/id/eprint/30325

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