Volkow, N. D., Levy, A., Brodie, J. D., Wolf, A. P., Cancro, R., Van Gelder, P., Henn, F. (May 1992) Low cerebellar metabolism in medicated patients with chronic schizophrenia. American Journal of Psychiatry, 149 (5). pp. 686-8. ISSN 0002-953X
Abstract
Because of the frequent association of cerebellar structural defects with schizophrenia, the authors reanalyzed the metabolic brain images of patients with chronic schizophrenia to assess if they had abnormalities in cerebellar metabolism. They used carbon-11-2-deoxyglucose and positron emission tomography to study 18 medicated patients with chronic schizophrenia and 12 normal comparison subjects. Patients with schizophrenia showed significantly lower absolute and relative metabolism in the cerebellum than normal subjects.
| Item Type: | Paper |
|---|---|
| Uncontrolled Keywords: | Adult Carbon Radioisotopes/diagnostic use Cerebellum/*metabolism/radionuclide imaging Deoxyglucose/diagnostic use Glucose/*metabolism Humans Middle Aged Psychiatric Status Rating Scales Schizophrenia/*diagnosis/metabolism Tomography, Emission-Computed |
| Subjects: | diseases & disorders > mental disorders > schizophrenia organs, tissues, organelles, cell types and functions > tissues types and functions > cerebellum organs, tissues, organelles, cell types and functions > organs types and functions > metabolism |
| CSHL Authors: | |
| Communities: | CSHL labs > Henn lab |
| Depositing User: | Matt Covey |
| Date: | May 1992 |
| Date Deposited: | 06 Jun 2014 20:17 |
| Last Modified: | 06 Jun 2014 20:17 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/30243 |
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