Low cerebellar metabolism in medicated patients with chronic schizophrenia

Volkow, N. D., Levy, A., Brodie, J. D., Wolf, A. P., Cancro, R., Van Gelder, P., Henn, F. (May 1992) Low cerebellar metabolism in medicated patients with chronic schizophrenia. American Journal of Psychiatry, 149 (5). pp. 686-8. ISSN 0002-953X

URL: http://www.ncbi.nlm.nih.gov/pubmed/1575261

Abstract

Because of the frequent association of cerebellar structural defects with schizophrenia, the authors reanalyzed the metabolic brain images of patients with chronic schizophrenia to assess if they had abnormalities in cerebellar metabolism. They used carbon-11-2-deoxyglucose and positron emission tomography to study 18 medicated patients with chronic schizophrenia and 12 normal comparison subjects. Patients with schizophrenia showed significantly lower absolute and relative metabolism in the cerebellum than normal subjects.

Item Type: Paper
Uncontrolled Keywords: Adult Carbon Radioisotopes/diagnostic use Cerebellum/*metabolism/radionuclide imaging Deoxyglucose/diagnostic use Glucose/*metabolism Humans Middle Aged Psychiatric Status Rating Scales Schizophrenia/*diagnosis/metabolism Tomography, Emission-Computed
Subjects: diseases & disorders > mental disorders > schizophrenia
organs, tissues, organelles, cell types and functions > tissues types and functions > cerebellum
organs, tissues, organelles, cell types and functions > organs types and functions > metabolism
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date: May 1992
Date Deposited: 06 Jun 2014 20:17
Last Modified: 06 Jun 2014 20:17
Related URLs:
URI: http://repository.cshl.edu/id/eprint/30243

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving