Cellular localization of [3H]-diazepam receptors

Henn, F. A., Henke, D. J. (November 1978) Cellular localization of [3H]-diazepam receptors. Neuropharmacology, 17 (11). pp. 985-8. ISSN 0028-3908 (Print)0028-3908

URL: http://www.ncbi.nlm.nih.gov/pubmed/724102
DOI: 10.1016/0028-3908(78)90143-0

Abstract

Isolated fractions enriched in bovine cortical astroglial cells or nerve endings were used to determine the receptor site for [3H]-diazepam binding. The results suggest strong enrichment in glial cells for the benzodiazepine receptor. Both the inhibition of diazepam binding by other benzodiazepines and the affinity of the glial receptor for diazepam suggest that this receptor is similar to that previously reported in crude CNS membrane fractions.

Item Type: Paper
Uncontrolled Keywords: Animals Brain/*metabolism Cattle Diazepam/*metabolism Nerve Endings/metabolism Neuroglia/metabolism Receptors, Drug/*analysis
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > glia cells

bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein receptor
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date: November 1978
Date Deposited: 09 Jul 2014 15:25
Last Modified: 09 Jul 2014 15:25
Related URLs:
URI: http://repository.cshl.edu/id/eprint/30215

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