Imaging calcium dynamics in dendritic spines

Denk, W., Yuste, R., Svoboda, K., Tank, D. W. (June 1996) Imaging calcium dynamics in dendritic spines. Curr Opin Neurobiol, 6 (3). pp. 372-8. ISSN 0959-4388

URL: http://www.ncbi.nlm.nih.gov/pubmed/8794079
DOI: 10.1016/S0959-4388(96)80122-X

Abstract

Recent advances in optical imaging technology have enabled the measurement of Ca2+ dynamics in individual synaptic spines with high time resolution. Results from work using this new technology have confirmed the view that individual synaptic spines can act as functional chemical compartments with independent dynamics of second-messenger concentration. In particular, the ability of Ca2+ to directly mediate Hebbian coincidence detection has been confirmed.

Item Type: Paper
Uncontrolled Keywords: Animals Calcium/*physiology Calcium Channels/physiology Dendrites/*metabolism/physiology/ultrastructure Electrophysiology Microscopy, Fluorescence *Optics Receptors, N-Methyl-D-Aspartate/metabolism Synapses/physiology Technology, Medical
Subjects: organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines
organs, tissues, organelles, cell types and functions > cell types and functions > cell types > dendritic cells > dendritic spines
CSHL Authors:
Communities: CSHL labs > Svoboda lab
Depositing User: Matt Covey
Date: June 1996
Date Deposited: 22 May 2014 14:46
Last Modified: 22 May 2014 14:46
Related URLs:
URI: http://repository.cshl.edu/id/eprint/30162

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