The G protein alpha subunit (GP alpha1) is associated with the ER and the plasma membrane in meristematic cells of Arabidopsis and cauliflower

Weiss, C. A., White, E., Huang, H., Ma, H. (1997) The G protein alpha subunit (GP alpha1) is associated with the ER and the plasma membrane in meristematic cells of Arabidopsis and cauliflower. Febs Letters, 407 (3). pp. 361-7. ISSN 0014-5793

URL: http://www.ncbi.nlm.nih.gov/pubmed/9175885
DOI: 10.1016/S0014-5793(97)00378-5

Abstract

Towards the elucidation of the cellular function(s) of GP alpha1, we have characterized its subcellular localization using immunofluorescence and cell fractionation. GP alpha1 is not present in nuclei or chloroplasts. It is a membrane-bound protein, and analysis of isolated endoplasmic and plasma membranes indicates a good correlation between GP alpha1 in both the plasma membrane and the ER compartment. Interestingly, these results may suggest more different functions for GP alpha1: it might be involved in transmission of extracellular signals across the plasma membrane and in the cytoplasm, and/or it may also be involved in regulating some aspects of the ER functions or membrane trafficking between both membranes.

Item Type: Paper
Uncontrolled Keywords: Arabidopsis/ metabolism Cell Compartmentation Cell Membrane/metabolism Endoplasmic Reticulum/metabolism Fluorescent Antibody Technique GTP-Binding Proteins/ metabolism Research Support, U.S. Gov't, Non-P.H.S. Signal Transduction Vegetables/ metabolism
Subjects: organism description > plant > Arabidopsis
organs, tissues, organelles, cell types and functions > organelles, types and functions > endoplasmic reticulum
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > GTP binding protein
organs, tissues, organelles, cell types and functions > tissues types and functions > signal transduction
CSHL Authors:
Communities: CSHL labs
Depositing User: Kathleen Darby
Date Deposited: 08 May 2014 15:52
Last Modified: 08 May 2014 15:52
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29990

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