A discrimination study of human core-promoters

Zhang, M. Q. (1998) A discrimination study of human core-promoters. Pacific Symposium on Biocomputing. pp. 240-51.

URL: http://www.ncbi.nlm.nih.gov/pubmed/9697186

Abstract

A core-promoter, approximately from -60 bp upstream to +40 bp downstream of a RNA polymerase (RNAP) II transcription start site (TSS), binds to the preinitiation complex (PIC) and determine the position of TSS. Using position-specific k-tuple feature variables, a quadratic discriminant analysis (QDA) method is shown to be very effective in identifying human core-promoters.

Item Type: Paper
Uncontrolled Keywords: Base Sequence Binding Sites Computational Biology/ methods Discriminant Analysis Humans Molecular Sequence Data Promoter Regions (Genetics) RNA Polymerase II/ genetics/ metabolism Reproducibility of Results Research Support, U.S. Gov't, P.H.S. Software TATA Box Transcription Factors/metabolism Transcription, Genetic
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > RNA polymerase
bioinformatics > computational biology
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > transcription factor
CSHL Authors:
Communities: CSHL labs > Zhang lab
Depositing User: Kathleen Darby
Date: 1998
Date Deposited: 30 Apr 2014 20:27
Last Modified: 30 Apr 2014 20:27
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29945

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