The Reactome pathway knowledgebase

Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., Hermjakob, H., Stein, L., D'Eustachio, P. (2014) The Reactome pathway knowledgebase. Nucleic Acids Research, 42 (Databa). D472-7. ISSN 0305-1048

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URL: http://www.ncbi.nlm.nih.gov/pubmed/24243840
DOI: 10.1093/nar/gkt1102

Abstract

Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.

Item Type: Paper
Uncontrolled Keywords: *Databases, Protein Disease Humans Internet Knowledge Bases Metabolic Networks and Pathways Proteins/*metabolism
Subjects: bioinformatics
bioinformatics > genomics and proteomics
bioinformatics > genomics and proteomics > databases > databases
bioinformatics > genomics and proteomics > datasets
CSHL Authors:
Communities: CSHL labs > Stein lab
Depositing User: Matt Covey
Date Deposited: 11 Apr 2014 18:38
Last Modified: 11 Apr 2014 18:38
PMCID: PMC3965010
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29749

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