Transgenerational Epigenetic Inheritance: Myths and Mechanisms

Heard, E., Martienssen, R. A. (March 2014) Transgenerational Epigenetic Inheritance: Myths and Mechanisms. Cell, 157 (1). pp. 95-109. ISSN 0092-8674

URL: http://www.ncbi.nlm.nih.gov/pubmed/24679529
DOI: 10.1016/j.cell.2014.02.045

Abstract

Since the human genome was sequenced, the term "epigenetics" is increasingly being associated with the hope that we are more than just the sum of our genes. Might what we eat, the air we breathe, or even the emotions we feel influence not only our genes but those of descendants? The environment can certainly influence gene expression and can lead to disease, but transgenerational consequences are another matter. Although the inheritance of epigenetic characters can certainly occur-particularly in plants-how much is due to the environment and the extent to which it happens in humans remain unclear.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > epigenetics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > epigenetics
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date: 27 March 2014
Date Deposited: 11 Apr 2014 19:38
Last Modified: 11 Apr 2014 19:38
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29736

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