Identification of Ras-regulated genes by representational difference analysis

Shields, J. M., Der, C. J., Powers, S. (2001) Identification of Ras-regulated genes by representational difference analysis. Methods in Enzymology, 332. pp. 221-32. ISSN 00766879 (ISSN)

URL: http://www.ncbi.nlm.nih.gov/pubmed/11305099
DOI: 10.1016/S0076-6879(01)32205-X

Abstract

In conclusion, RDA provides a fast, technically simple, and inexpensive way to characterize genes aberrantly expressed due to Ras transformation. The identification and characterization of these genes may provide insight not only into the mechanism by which Ras causes transformation, but also may identify novel targets for rational drug design and development of anticancer drugs.

Item Type: Paper
Uncontrolled Keywords: Animals Base Sequence Cell Line Cloning, Molecular DNA Primers/genetics DNA, Complementary/genetics/isolation & purification Down-Regulation Gene Expression Regulation *Genes, ras *Genetic Techniques Nucleic Acid Hybridization Polymerase Chain Reaction RNA, Messenger/genetics/isolation & purification Rats
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > G protein > Ras
CSHL Authors:
Communities: CSHL labs > Powers lab
Depositing User: Matt Covey
Date: 2001
Date Deposited: 25 Feb 2014 21:37
Last Modified: 25 Feb 2014 21:37
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29530

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