Ivy, J. M., Hicks, J. B., Klar, A. J.
(December 1985)
Map positions of yeast genes SIR1, SIR3 and SIR4.
Genetics, 111 (4).
pp. 735-44.
ISSN 0016-6731 (Print)0016-6731 (Linking)
Abstract
The HML and HMR loci in the yeast Saccharomyces cerevisiae each contain a complete copy of mating-type information. HML and HMR normally are transcriptionally inactive due to four unlinked genes, known as MAR or SIR or CMT. The map position of MAR1 (SIR2) has been reported previously; it is located on the left arm of chromosome IV, 27 cM from the centromere. Using conventional meiotic and mitotic mapping combined with recombinant DNA techniques, we have mapped three other SIR genes. SIR1 maps near the telomere of the right arm of chromosome XI; SIR3 (MAR2) maps to the right arm of chromosome XII, 31 cM distal to URA4; and SIR4 maps to the right arm of chromosome IV, 16 cM proximal to LYS4.
| Item Type: |
Paper
|
| Uncontrolled Keywords: |
Alleles
Chromosome Mapping
Cloning, Molecular
Crosses, Genetic
Genes, Fungal
Genes, Mating Type, Fungal
Meiosis
Mitosis
Plasmids
Saccharomyces cerevisiae/cytology/ genetics |
| Subjects: |
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organism description > yeast |
| CSHL Authors: |
|
| Communities: |
CSHL labs > Hicks lab |
| Depositing User: |
Matt Covey
|
| Date: |
December 1985 |
| Date Deposited: |
06 Feb 2014 17:23 |
| Last Modified: |
06 Feb 2014 17:23 |
| PMCID: |
PMC1202668 |
| Related URLs: |
|
| URI: |
https://repository.cshl.edu/id/eprint/29481 |
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