Transcriptional regulation: RUPture in the ER

Tansey, W. P. (October 2000) Transcriptional regulation: RUPture in the ER. Nature Cell Biology, 2 (10). E175-E177. ISSN 1465-7392

URL: http://www.ncbi.nlm.nih.gov/pubmed/11025674
DOI: 10.1038/35036420

Abstract

Regulated ubiquitin/proteasome-dependent processing controls transcription by triggering the release of dormant transcriptional activators from the endoplasmic reticulum. This intersection of transcription and proteolysis has important implications for gene control, proteasome-substrate interactions and signal integration.

Item Type: Paper
Uncontrolled Keywords: UBIQUITIN-PROTEASOME PATHWAY NF-KAPPA-B PROTEIN ACTIVATION RSP5
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
organs, tissues, organelles, cell types and functions > organelles, types and functions > endoplasmic reticulum
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein ubiquitination
CSHL Authors:
Communities: CSHL labs > Tansey lab
Depositing User: Matt Covey
Date: October 2000
Date Deposited: 28 Jan 2014 21:48
Last Modified: 28 Jan 2014 21:48
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29452

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