Inducing gene expression in barrel cortex - focus on immediate early genes

Filipkowski, R. K. (2000) Inducing gene expression in barrel cortex - focus on immediate early genes. Acta Neurobiologiae Experimentalis, 60 (3). pp. 411-418. ISSN 0065-1400

URL: http://www.ncbi.nlm.nih.gov/pubmed/11016084

Abstract

Using only their vibrissae, rats and mice are able to recognize and differentiate surfaces not distinguishable by primates using their fingertips. It has been shown that sensory stimulation elicits the expression of immediate-early genes (IEG), e.g., c-fos and zif268, in the sensory cortex of rats and mice. Though most of these findings come from visual system, mice and rats rely more on their vibrissal system which also offers many advantages for designing precise and precisely controlled experiments. In this review, new models for the selective and simple stimulation of vibrissae are presented and discussed. The data demonstrating IEG expression in the vibrissal system is also reviewed.

Item Type: Paper
Uncontrolled Keywords: c-Fos Zif268 sensory stimulation learning and memory plasticity parvalbumin FOS PROTOONCOGENE EXPRESSION TRANSCRIPTION FACTOR ZIF268 RAT SOMATOSENSORY CORTEX LASTING AP-1 COMPLEX C-FOS NERVOUS-SYSTEM VISUAL-CORTEX MESSENGER-RNA ROUGHNESS DISCRIMINATION THROMBOTIC INFARCTION
Subjects: organs, tissues, organelles, cell types and functions > tissues types and functions > barrel cortex
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > immediate early genes
CSHL Authors:
Communities: CSHL labs > Yin lab
Depositing User: Matt Covey
Date: 2000
Date Deposited: 30 Jan 2014 16:38
Last Modified: 30 Jan 2014 16:38
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29405

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