Genome annotation: From sequence to biology

Stein, L. (2001) Genome annotation: From sequence to biology. Nature Reviews Genetics, 2 (7). pp. 493-503. ISSN 1471-0056

URL: http://www.ncbi.nlm.nih.gov/pubmed/11433356
DOI: 10.1038/35080529

Abstract

The genome sequence of an organism is an information resource unlike any that biologists have previously had access to. But the value of the genome is only as good as its annotation. It is the annotation that bridges the gap from the sequence to the biology of the organism. The aim of high-quality annotation is to identify the key features of the genome - in particular, the genes and their products. The tools and resources for annotation are developing rapidly, and the scientific community is becoming increasingly reliant on this information for ail aspects of biological research.

Item Type: Paper
Uncontrolled Keywords: PROTEIN-CODING REGIONS TRANSFER-RNA GENES CAENORHABDITIS-ELEGANS DROSOPHILA-MELANOGASTER DISCRIMINANT-ANALYSIS LENS CRYSTALLINS DATABASE DNA IDENTIFICATION FAMILIES
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > genomes > genome annotation
CSHL Authors:
Communities: CSHL labs > Stein lab
Depositing User: Matt Covey
Date Deposited: 16 Jan 2014 17:17
Last Modified: 16 Jan 2014 17:17
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29307

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