How the worm removes corpses: the nematode C-elegans as a model system to study engulfment

Gumienny, T. L., Hengartner, M. O. (June 2001) How the worm removes corpses: the nematode C-elegans as a model system to study engulfment. Cell Death and Differentiation, 8 (6). pp. 564-568. ISSN 1350-9047

URL: http://www.ncbi.nlm.nih.gov/pubmed/11536006
DOI: 10.1038/sj/cdd/4400850

Abstract

Apoptotic with the removal of the dying cells from the organism. This removal is brought forth through a rapid and specific engulfment of the doomed cell by one of its neighbors. Over half a dozen genes have been identified that function in this process in the worm. Many of these engulfment genes have functional homologs in Drosophila and higher vertebrates. Indeed, there is growing evidence supporting the hypothesis that the pathways that mediate the removal of apoptotic cells might be, at least in part, conserved through evolution.

Item Type: Paper
Uncontrolled Keywords: apoptosis phagocytosis cell migration genetics rac PROGRAMMED CELL-DEATH CAENORHABDITIS-ELEGANS APOPTOTIC CELLS ABC TRANSPORTERS PROTEIN CED-6 GENE CED-7 PHAGOCYTOSIS HOMOLOG PHOSPHATIDYLSERINE IDENTIFICATION
Subjects: organism description > animal > C elegans
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > apoptosis
CSHL Authors:
Communities: CSHL labs > Hengartner lab
Depositing User: Matt Covey
Date: June 2001
Date Deposited: 22 Jan 2014 18:00
Last Modified: 22 Jan 2014 18:00
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29239

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