A scientific opportunity

Gershon, E. S., Kelsoe, J. R., Kendler, K. S., Watson, J. D. (November 2001) A scientific opportunity. Science, 294 (5544). p. 957. ISSN 0036-8075

URL: http://www.ncbi.nlm.nih.gov/pubmed/11691955
DOI: 10.1126/science.294.5544.957

Abstract

The discovery of susceptibility genes for bipolar disorder and schizophrenia is thought to be one of the most intractable current problems in human genetics. The epidemiological data argue that a substantial portion of the genetic variance seen in these disorders results from a limited number of genes with small effects. This is similar to the situation for many other common diseases with complex inheritance patterns. Nevertheless, recent scientific advances in human genetics, combined with recent findings on bipolar disorder and schizophrenia and the availability of family samples through the U.S. National Institute of Mental Health (NIMH) (www-grb.nimh.nih.gov/gi.html), suggest that a scientific opportunity now exists to identify susceptibility genes for these disorders.

Item Type: Paper
Subjects: diseases & disorders > mental disorders > anxiety disorders
diseases & disorders > mental disorders
diseases & disorders > mental disorders > mood disorders
diseases & disorders > mental disorders > schizophrenia
diseases & disorders > mental disorders > mood disorders > depression
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > gene expression
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
CSHL Authors:
Communities: CSHL labs
Depositing User: Matt Covey
Date: November 2001
Date Deposited: 22 Jan 2014 17:53
Last Modified: 22 Jan 2014 17:53
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29237

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