AgrobacteriumT-DNA-encoded protein Atu6002 interferes with the host auxin response

Lacroix, B., Gizatullina, D. I., Babst, B. A., Gifford, A. N., Citovsky, V. (April 2014) AgrobacteriumT-DNA-encoded protein Atu6002 interferes with the host auxin response. Molecular Plant Pathology, 15 (3). pp. 275-283. ISSN 14646722 (ISSN)

URL: http://www.ncbi.nlm.nih.gov/pubmed/24128370
DOI: 10.1111/mpp.12088

Abstract

Several genes in the Agrobacterium tumefaciens transferred (T)-DNA encode proteins that are involved in developmental alterations, leading to the formation of tumours in infected plants. We investigated the role of the protein encoded by the Atu6002 gene, the function of which is completely unknown. Atu6002 expression occurs in Agrobacterium-induced tumours, and is also activated on activation of plant cell division by growth hormones. Within the expressing plant cells, the Atu6002 protein is targeted to the plasma membrane. Interestingly, constitutive ectopic expression of Atu6002 in transgenic tobacco plants leads to a severe developmental phenotype characterized by stunted growth, shorter internodes, lanceolate leaves, increased branching and modified flower morphology. These Atu6002-expressing plants also display impaired response to auxin. However, auxin cellular uptake and polar transport are not significantly inhibited in these plants, suggesting that Atu6002 interferes with auxin perception or signalling pathways. © 2013 BSPP AND JOHN WILEY & SONS LTD.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organism description > plant
CSHL Authors:
Communities: CSHL labs > Zador lab
Depositing User: Matt Covey
Date: April 2014
Date Deposited: 23 Dec 2013 19:56
Last Modified: 24 Dec 2014 14:49
PMCID: PMC3949161
Related URLs:
URI: http://repository.cshl.edu/id/eprint/29159

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving