Chipping away at chromatin

Martienssen, R. (2001) Chipping away at chromatin. Nature Genetics, 27 (3). pp. 240-241. ISSN 1061-4036

URL: http://www.ncbi.nlm.nih.gov/pubmed/11242099
DOI: 10.1038/85787

Abstract

When DNA-binding proteins are tethered to dam methylase from Escherichia coli. adenine methylation is directed to eukaryotic target sites in vivo. Hybridization of methylated DNA to microarrays allows binding sites to be displayed genome-wide, providing a versatile alternative to chromatin immunoprecipitation.

Item Type: Paper
Uncontrolled Keywords: in-vivo methyltransferase probe
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > DNA methylation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > DNA binding protein
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date Deposited: 13 Dec 2013 16:18
Last Modified: 13 Dec 2013 16:18
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28988

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