The FRUITFULL MADS-box gene mediates cell differentiation during Arabidopsis fruit development

Gu, Q., Ferrandiz, C., Yanofsky, M. F., Martienssen, R. (April 1998) The FRUITFULL MADS-box gene mediates cell differentiation during Arabidopsis fruit development. Development, 125 (8). pp. 1509-1517. ISSN 0950-1991

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URL: http://www.ncbi.nlm.nih.gov/pubmed/9502732

Abstract

Fruit morphogenesis is a process unique to flowering plants, and yet little is known about its developmental control, Following fertilization, fruits typically undergo a dramatic enlargement that is accompanied by differentiation of numerous distinct cell types. We have identified a mutation in Arabidopsis called fruitfull (ful-1), which abolishes elongation of the silique after fertilization. The ful-1 mutation is caused by the insertion of a DsE transposable enhancer trap element into the 5' untranslated leader of the AGL8 MADS-box gene. beta-glucuronidase (GUS) reporter gene expression in the enhancer trap line is observed specifically in all cell layers of the valve tissue, but not in the replum, the septum or the seeds, and faithfully mimics RNA in situ hybridization data reported previously, The lack of coordinated growth of the fruit tissues leads to crowded seeds, a failure of dehiscence and, frequently, the premature rupture of the carpel valves, The primary defect of ful-1 fruits is within the valves, whose cells fail to elongate and differentiate. Stomata, which are frequent along the epidermis of wild-type valves, are completely eliminated in the ful mutant valves. In addition to the effect on fruit development, ful cauline leaves are broader than those of wild type and show a reduction in the number of internal cell layers. These data suggest that AGL8/FUL regulates the transcription of genes required for cellular differentiation during fruit and leaf development.

Item Type: Paper
Uncontrolled Keywords: ful fruit development MADS-box gene cell division and expansion transposable enhancer trap Arabidopsis thaliana flower development inflorescence meristems thaliana apetala1 mutation leaf trap
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > cell division
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions
organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > differentiation
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organism description > plant
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date: April 1998
Date Deposited: 13 Dec 2013 16:46
Last Modified: 13 Dec 2013 16:46
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28976

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