Electroconvulsive therapy in a patient receiving rivastigmine

Zink, M., Sartorius, A., Lederbogen, F., Henn, F. A. (2002) Electroconvulsive therapy in a patient receiving rivastigmine. Journal of ECT, 18 (3). pp. 162-4. ISSN 1095-0680 (Print)1095-0680 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/12394536


We report the case of an 81-year-old woman, suffering from a major depressive episode and incipient Alzheimer disease, whom we treated with ECT without interrupting therapy with the acetylcholinesterase inhibitor (ACHE-I) rivastigmine. After eight right unilateral ECT sessions, the patient remitted completely without any significant deterioration of memory and cognitive abilities or cholinergic side effects. This report demonstrates that ECT was safely used in one elderly and mildly demented person with continuous ACHE-I therapy. The hypothesis that this drug may indeed protect against unfavorable side effects of ECT should be further tested in clinical trials.

Item Type: Paper
Uncontrolled Keywords: Aged Aged, 80 and over Alzheimer Disease/complications/ drug therapy Carbamates/ therapeutic use Cholinesterase Inhibitors/ therapeutic use Depressive Disorder, Major/complications/ therapy Electroconvulsive Therapy Female Humans Phenylcarbamates Safety Treatment Outcome
Subjects: diseases & disorders > mental disorders > delirium dementia cognitive disorders > Alzheimer's disease
diseases & disorders > mental disorders > delirium dementia cognitive disorders
diseases & disorders
CSHL Authors:
Communities: CSHL labs > Henn lab
Depositing User: Matt Covey
Date Deposited: 16 Oct 2013 20:01
Last Modified: 16 Oct 2013 20:01
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28824

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