The homeobox gene BREVIPEDICELLUS is a key regulator of inflorescence architecture in Arabidopsis

Venglat, S. P., Dumonceaux, T., Rozwadowski, K., Parnell, L., Babic, V., Keller, W., Martienssen, R., Selvaraj, G., Datla, R. (April 2002) The homeobox gene BREVIPEDICELLUS is a key regulator of inflorescence architecture in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 99 (7). pp. 4730-5. ISSN 0027-8424 (Print)0027-8424 (Linking)

URL: http://www.ncbi.nlm.nih.gov/pubmed/11917137
DOI: 10.1073/pnas.072626099

Abstract

Flowering plants display a remarkable range of inflorescence architecture, and pedicel characteristics are one of the key contributors to this diversity. However, very little is known about the genes or the pathways that regulate pedicel development. The brevipedicellus (bp) mutant of Arabidopsis thaliana displays a unique phenotype with defects in pedicel development causing downward-pointing flowers and a compact inflorescence architecture. Cloning and molecular analysis of two independent mutant alleles revealed that BP encodes the homeodomain protein KNAT1, a member of the KNOX family. bp-1 is a null allele with deletion of the entire locus, whereas bp-2 has a point mutation that is predicted to result in a truncated protein. In both bp alleles, the pedicels and internodes were compact because of fewer cell divisions; in addition, defects in epidermal and cortical cell differentiation and elongation were found in the affected regions. The downward-pointing pedicels were produced by an asymmetric effect of the bp mutation on the abaxial vs. adaxial sides. Cell differentiation, elongation, and growth were affected more severely on the abaxial than adaxial side, causing the change in the pedicel growth angle. In addition, bp plants displayed defects in cell differentiation and radial growth of the style. Our results show that BP plays a key regulatory role in defining important aspects of the growth and cell differentiation of the inflorescence stem, pedicel, and style in Arabidopsis.

Item Type: Paper
Uncontrolled Keywords: Amino Acid Sequence Arabidopsis genetics growth & development Arabidopsis Proteins Base Sequence Cell Differentiation Cell Division Genes, Homeobox Genes Plant physiology Homeodomain Proteins genetics Molecular Sequence Data Phenotype Plant Proteins genetics
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
organs, tissues, organelles, cell types and functions > tissues types and functions > inflorescence
CSHL Authors:
Communities: CSHL labs > Martienssen lab
Depositing User: Matt Covey
Date: 2 April 2002
Date Deposited: 16 Oct 2013 20:31
Last Modified: 16 Oct 2013 20:31
PMCID: PMC123716
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28804

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