Direction of motion maps in the visual cortex: a wire length minimization approach

Koulakov, A. A., Chklovskii, D. B. (2002) Direction of motion maps in the visual cortex: a wire length minimization approach. Neurocomputing, 44. pp. 489-494. ISSN 0925-2312

URL: http://www.sciencedirect.com/science/article/pii/S...
DOI: 10.1016/S0925-2312(02)00406-X

Abstract

In the visual cortex, many neurons respond preferentially to one direction of motion. Maps of direction preference vary in appearance between species and cortical areas. We propose that the observed variability in map appearance reflect the variability in intra-cortical circuits as a consequence of wire length minimization. This hypothesis allows us to bypass a detailed developmental analysis of map formation. We solve the layout optimization problem numerically for various intra-cortical circuits and obtain direction preference maps that reproduce the observed variability in map appearance. These results allow one to infer intra-cortical connectivity from the appearance of direction preference maps.

Item Type: Paper
Uncontrolled Keywords: Visual cortex Wire length Maps
Subjects: bioinformatics > computational biology
organs, tissues, organelles, cell types and functions > tissues types and functions
organs, tissues, organelles, cell types and functions > tissues types and functions > visual cortex
CSHL Authors:
Communities: CSHL labs > Koulakov lab
Depositing User: Matt Covey
Date Deposited: 19 Dec 2013 19:40
Last Modified: 19 Dec 2013 19:40
URI: http://repository.cshl.edu/id/eprint/28731

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