Heterochromatin: new possibilities for the inheritance of structure

Grewal, S. I. S., Elgin, S. C. (2002) Heterochromatin: new possibilities for the inheritance of structure. Current Opinion in Genetics & Development, 12 (2). pp. 178-187. ISSN 0959-437X

URL: http://www.ncbi.nlm.nih.gov/pubmed/11893491
DOI: 10.1016/S0959-437X(02)00284-8

Abstract

Significant portions of the eukaryotic genome are heterochromatic, made up largely of repetitious sequences and possessing a distinctive chromatin structure associated with gene silencing. New insights into the form of packaging, the associated histone modifications, and the associated nonhistone chromosomal proteins of heterochromatin have suggested a mechanism for providing an epigenetic mark that allows this distinctive chromatin structure to be maintained following replication and to spread within a given domain.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > Chromatin dynamics > heterochromatin
CSHL Authors:
Communities: CSHL labs > Grewal lab
Depositing User: Matt Covey
Date Deposited: 08 Jan 2014 21:30
Last Modified: 08 Jan 2014 21:30
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28708

Actions (login required)

Administrator's edit/view item Administrator's edit/view item
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving