Tumour suppression: something for nothing?

de Stanchina, E., Lowe, S. W. (December 2002) Tumour suppression: something for nothing? Nature Cell Biology, 4 (12). E275-E276. ISSN 1465-7392

URL: http://www.ncbi.nlm.nih.gov/pubmed/12461528
DOI: 10.1038/ncb1202-e275

Abstract

Increasing the activity of the p53 tumour suppressor in mice protects them from cancer, but this has also been associated with an unwanted side effect, specifically, premature ageing. However, a new strain of 'super p53' mice are resistant to cancer but age gracefully, suggesting that protection from cancer doesn't always come at a price.

Item Type: Paper
Subjects: bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > tumor suppressor
CSHL Authors:
Communities: CSHL labs > Lowe lab
Depositing User: Matt Covey
Date: December 2002
Date Deposited: 08 Jan 2014 21:46
Last Modified: 08 Jan 2014 21:46
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28693

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