de Stanchina, E., Lowe, S. W. (December 2002) Tumour suppression: something for nothing? Nature Cell Biology, 4 (12). E275-E276. ISSN 1465-7392
DOI: 10.1038/ncb1202-e275
Abstract
Increasing the activity of the p53 tumour suppressor in mice protects them from cancer, but this has also been associated with an unwanted side effect, specifically, premature ageing. However, a new strain of 'super p53' mice are resistant to cancer but age gracefully, suggesting that protection from cancer doesn't always come at a price.
| Item Type: | Paper |
|---|---|
| Subjects: | bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > tumor suppressor |
| CSHL Authors: | |
| Communities: | CSHL labs > Lowe lab |
| Depositing User: | Matt Covey |
| Date: | December 2002 |
| Date Deposited: | 08 Jan 2014 21:46 |
| Last Modified: | 08 Jan 2014 21:46 |
| Related URLs: | |
| URI: | https://repository.cshl.edu/id/eprint/28693 |
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