Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor

Onai, T., FitzGerald, M. G., Arakawa, S., Gocayne, J. D., Urquhart, D. A., Hall, L. M., Fraser, C. M., McCombie, W. R., Venter, J. C. (1989) Cloning, sequence analysis and chromosome localization of a Drosophila muscarinic acetylcholine receptor. FEBS Letters, 255 (2). pp. 219-225. ISSN 00145793 (ISSN)

URL: http://www.ncbi.nlm.nih.gov/pubmed/2507354
DOI: 10.1016/0014-5793(89)81095-6

Abstract

Two cDNA clones (3.7 kb and 4.8 kb) encoding a Drosophila muscarinic acetylcholine receptor were isolated from a Drosophila head cDNA library and characterized by automated DNA sequence analysis. The Drosophila muscarinic receptor contains 788 amino acids with a calculated Mr of 84 807 and displays greater than 60% homology with mammalian muscarinic receptors. The muscarinic receptor maps to the tip of the right arm of the second chromosome of the Drosophila genome. © 1989.

Item Type: Paper
Uncontrolled Keywords: cDNA DNA sequence analysis, automated Receptor evolution Receptor supergene family Sequence homology Signal sequence DNA muscarinic receptor amino acid sequence animal article chromosome map comparative study computer program Drosophila melanogaster genetics molecular cloning molecular genetics nucleotide sequence protein conformation restriction mapping structural gene Base Sequence Chromosome Mapping Cloning, Molecular Genes, Structural Molecular Sequence Data Receptors, Muscarinic Sequence Homology, Nucleic Acid Software Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S.
Subjects: bioinformatics > genomics and proteomics > analysis and processing
bioinformatics
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification
organism description > animal > insect > Drosophila
bioinformatics > genomics and proteomics > genetics & nucleic acid processing
bioinformatics > genomics and proteomics
Investigative techniques and equipment
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification
Investigative techniques and equipment > assays
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosome
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function > chromosome

bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > chromosomes, structure and function
Investigative techniques and equipment > cloning
Investigative techniques and equipment > assays > cloning

organism description > animal > insect
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein receptor
CSHL Authors:
Communities: CSHL labs > McCombie lab
Depositing User: Matt Covey
Date Deposited: 25 Apr 2013 17:56
Last Modified: 25 Apr 2013 17:56
Related URLs:
URI: http://repository.cshl.edu/id/eprint/28200

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